지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.6
- 수록면
- 138 - 143 (6page)
이용수
초록· 키워드
오류제보하기
Objective: To evaluate the short-term effect of fangchinoline, an antiinflammatory drug widely used in Asia, on root resorption that is associated with orthodontic tooth movement. Methods: Twenty-four Wistar rats were randomly divided into 6 groups. Mesial forces of 0, 50, or 100 g were applied to the maxillary first molar of the rats in each group for 14 days by activating nickel-titanium closed-coil springs. One-half of the rats receiving each of these treatments also received injections of 200 μL fangchinoline every 2 days. Finally, movement of the maxillary first molars was measured using digitized radiographs. The molars were extracted and the surfaces of the root resorption craters were recorded using a scanning electron microscope. The distance the molars moved and resorptionarea ratio was measured, and results were analyzed using 2-way ANOVA tests. Results: There were no statistical differences in the distances the first molars moved under 50 or 100 g force, regardless of treatment with fangchinoline. However, the resorption area ratios were significantly smaller in those rats that were treated with both tension and fangchinoline than in those rats treated by tension alone. Conclusions: Fangchinoline reduced the resorption area ratio in rats and is therefore an important means of alleviating root resorption.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
CONCLUSION
REFERENCES
참고문헌 (21)
참고문헌 신청
Brudvik P / 1993 / Non-clast cells start orthodontic root resorption in the periphery of hyalinized zones / Eur J Orthod 15:467~480
Segal GR / 2004 / Meta analysis of the treatment-related factors of external apical root resorption / Orthod Craniofac Res 7:71~78
Sringkarnboriboon S / 2003 / Root resorption related to hypofunctional periodontium in experimental tooth movement / J Dent Res 82:486~490
Harokopakis-Hajishengallis E / 2007 / Physiologic root resorption in primary teeth: molecular and histological events / J Oral Sci 49:1~12
Meikle MC. / 2006 / The tissue, cellular, and molecular regulation of orthodontic tooth movement: 100 years aft er Carl Sandstedt / Eur J Orthod 28:221~240
Segal GR / 2004 / Meta analysis of the treatment-related factors of external apical root resorption / Orthod Craniofac Res 7:71~78
Sringkarnboriboon S / 2003 / Root resorption related to hypofunctional periodontium in experimental tooth movement / J Dent Res 82:486~490
Harokopakis-Hajishengallis E / 2007 / Physiologic root resorption in primary teeth: molecular and histological events / J Oral Sci 49:1~12
Meikle MC. / 2006 / The tissue, cellular, and molecular regulation of orthodontic tooth movement: 100 years aft er Carl Sandstedt / Eur J Orthod 28:221~240
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UCI(KEPA) : I410-ECN-0101-2014-515-000447617