지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.89 No.3
- 발행연도
- 2015.8
- 수록면
- 124 - 130 (7page)
이용수
초록· 키워드
오류제보하기
Purpose: Although adjuvant chemotherapy reduces the risk of disease recurrence in stage Ⅲ colon cancer patients, published guidelines do not specify when it should be initiated. This study aimed to assess the effect of adjuvant chemotherapy initiation time on disease recurrence and survival in stage Ⅲ colon cancer patients undergoing curative surgical resection.
Methods: The medical records of stage Ⅲ colon cancer patients undergoing curative resection between February 2004 and December 2009 were reviewed.
Results: Of the 133 enrolled patients, 27 (20.3%) began adjuvant chemotherapy within 3 weeks of surgery, whereas 106 (79.7%) did after 3 weeks following surgery. Patients receiving chemotherapy within 3 weeks of surgery were less likely to experience recurrences than those beginning treatment later (11.1% vs. 33%, P = 0.018). The mean disease-free survival of patients receiving adjuvant therapy earlier was 54.6 months, whereas that of patients with later treatment was 43.5 months (P = 0.014). However, no significant differences in overall survival were observed between the 2 groups.
Conclusion: Adjuvant chemotherapy should be initiated as soon as a patient’s clinical condition allows. Patients with stage Ⅲ colon cancer may benefit from adjuvant chemotherapy initiated within 3 weeks of surgery.
Methods: The medical records of stage Ⅲ colon cancer patients undergoing curative resection between February 2004 and December 2009 were reviewed.
Results: Of the 133 enrolled patients, 27 (20.3%) began adjuvant chemotherapy within 3 weeks of surgery, whereas 106 (79.7%) did after 3 weeks following surgery. Patients receiving chemotherapy within 3 weeks of surgery were less likely to experience recurrences than those beginning treatment later (11.1% vs. 33%, P = 0.018). The mean disease-free survival of patients receiving adjuvant therapy earlier was 54.6 months, whereas that of patients with later treatment was 43.5 months (P = 0.014). However, no significant differences in overall survival were observed between the 2 groups.
Conclusion: Adjuvant chemotherapy should be initiated as soon as a patient’s clinical condition allows. Patients with stage Ⅲ colon cancer may benefit from adjuvant chemotherapy initiated within 3 weeks of surgery.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Adjuvant chemotherapy for patients with stage II high-risk and III colon cancer: Hindering factors to adherence and impact on long-term survival
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2021 .06
-
Adjuvant Chemotherapy
대한외과학회 학술대회 초록집
2021 .11
-
Adjuvant chemotherapy in patients with stage II colon cancer
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2018 .12
-
70세 이상의 노인 대장암 환자의 수술 후 보조요법의 위험 인자와 효과
Annals of geriatric medicine and research
2015 .01
-
The efficacy of chemotherapy in the patients with stage II colon cancer associated with number of high-risk factors
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2018 .12
-
Comparison of the Beneficial Effects of Adjuvant Chemotherapy among Young and Old Aged Breast Cancer Patients
Journal of Breast Disease
2019 .01
-
Adjuvant Chemotherapy and Prognostic Factors in Stage II Colon Cancer - Izmir Oncology Group Study
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Comparing the initiation of adjuvant chemotherapy after robotic and laparoscopic colon cancer surgeries: A case-controlled study with propensity score matching
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2020 .06
-
Quality of life changes during adjuvant chemotherapy in patients with colon cancer
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2016 .06
-
Is Adjuvant Chemotherapy Beneficial for Oldest-old (Aged 80 Years or Older) Patients with Stage II Colon Cancer?
대한외과학회 학술대회 초록집
2020 .11
-
Evaluation of the Survival Benefit of Different Chemotherapy Regimens in Patients with T1-2N0 Triple-Negative Breast Cancer
Journal of Breast Cancer
2015 .01
-
The Effect of Adjuvant Chemotherapy in the Elderly Patients Receiving Colorectal Cancer Surgeries: A Propensity Score-Matched Analysis
대한외과학회 학술대회 초록집
2021 .05
-
The Role of Adjuvant Therapy Following Surgical Resection of Small Cell Lung Cancer: A Multi-Center Study
Cancer Research and Treatment
2023 .01
-
Effect of Adjuvant Chemotherapy on Stage II Colon Cancer: Analysis of Korean National Data
Cancer Research and Treatment
2018 .01
-
The Prognosis and the Role of Adjuvant Chemotherapy for Node-Positive Bladder Cancer Treated with Neoadjuvant Chemotherapy Followed by Surgery
Cancer Research and Treatment
2022 .01
-
Adjuvant Chemotherapy for Pancreatic Cancer
대한외과학회 학술대회 초록집
2022 .05
-
The impact of interval between primary cytoreductive surgery with bowel resection and initiation of adjuvant chemotherapy on survival of women with advanced ovarian cancer: a multicenter cohort study
Journal of Gynecologic Oncology
2022 .11
-
The Effect of Adjuvant Chemotherapy for Stage IIa(T3N0) Colon Cancer
대한임상종양학회 학술대회지
2016 .02
-
Effect of age on laparoscopic surgery and adjuvant chemotherapy in elderly colorectal cancer patients
대한외과학회 학술대회 초록집
2019 .10
이 논문의 저자 정보
이 논문과 함께 이용한 논문
Quality of life changes during adjuvant chemotherapy in patients with colon cancer
Seo Hee Lee
,
Taek-Gu Lee
,
Moo Jun Baek
외 4명
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2016
.06
Ethanol extract of Innotus obliquus (Chaga mushroom) induces G1 cell cycle arrest in HT-29 human colon cancer cells
Hyun Sook Lee
,
Eun Ji Kim
,
Sun Hyo Kim
Nutrition Research and Practice
2015
.04
ADJUVANT CHEMOTHERAPY FOR COLORECTAL CANCER
JAE KYUNG ROH
대한외과학회 학술대회 초록집
1989
.11
Adjuvant Chemotherapy for Gastric Cancer
Sung Soo Pa
,
k
대한임상종양학회 학술대회지
2008
.11
최근 본 자료
댓글(0)
0