Study on Causes of Respiratory Disease to the Middle East Respiratory Syndrome-negative Subjects

Su-Jeong Hwang; Dong-Ju Park; Hee-Soo Koo; Ho-Cheol Yun; Pyeung-Tae Gu; Mi-Ok Lee; Sung-Hyun Jin

추천

검색

질문

자료유형: 학술저널

저자정보: Su-Jeong Hwang (Busan Metropolitan City Institute of Health & Environment) Dong-Ju Park (Busan Metropolitan City Institute of Health & Environment) Hee-Soo Koo (Busan Metropolitan City Institute of Health & Environment) Ho-Cheol Yun (Busan Metropolitan City Institute of Health & Environment) Pyeung-Tae Gu (Busan Metropolitan City Institute of Health & Environment) Mi-Ok Lee (Busan Metropolitan City Institute of Health & Environment) Sung-Hyun Jin (Busan Metropolitan City Institute of Health & Environment)

저널정보: 대한바이러스학회 JOURNAL OF BACTERIOLOGY AND VIROLOGY JOURNAL OF BACTERIOLOGY AND VIROLOGY Vol.47 No.3

발행연도: 2017.9

수록면: 156 - 164 (9page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe cases of human respiratory disease. The current outbreak of infection with this virus in South Korea, which began on May 20, 2015, has infected 186 patients and caused 36 deaths within 2 months. In this study, to investigate the viral pathogen causing acute respiratory infections, multiplex/RT-PCR was performed on were obtained from nucleic acid of the Middle East Respiratory Syndrome-negative subjects. Viruses and atypical bacteria were detected in 39 of 337 (11.6%). Frequent viruses were human rhinovirus (n=11, 3.3%), human metapneumovirus (n=9, 2.7%), parainfluenza (n=9, 2.7%) and adenovirus (n=4, 1.2%). Mycoplasma pneumonia (M. pneumonia) was detected in 1.8 % (n=6). Out of 9 human metapneumovirus (hMPV) positive samples, 6 samples were successfully sequenced using F gene. And M. pneumoniae was sequencing of a repetitive region of the P1 gene. Phylogenetic analysis revealed that hMPV clustered into A2b lineage (n=4), B2 lineage (n=2) and M. pneumoniae clustered into two genotypes: Type 1 (n=4), Type 2a (n=2).

#Middle East respiratory syndrome coronavirus (MERS-CoV) #Human Metapneumovirus (hMPV) #Mycoplasma pneumonia (M. pneumonia) #Phylogenetic analysis

참고문헌 (27)

참고문헌 신청

[인터넷자원] - World Health Organization / / Middle East respiratory syndrome coronavirus (MERS-CoV) global summary and risk assessment

[학술지(정기간행물)] - Zumla A / 2015 / Middle East respiratory syndrome / Lancet 386 : 995 ~ 1007

[학술지(정기간행물)] - Reiche J / 2014 / Human metapneumovirus: insights from a ten-year molecular and epidemiological analysis in Germany / PLoS One 9 : e88342 ~

[학술지(정기간행물)] - Dumke R / 2006 / Culture-independent molecular subtyping of Mycoplasma pneumoniae in clinical samples / J Clin Microbiol 44 : 2567 ~ 2570

[학술지(정기간행물)] - Mackay IM / 2008 / Human rhinoviruses: the cold wars resume / J Clin Virol 42 : 297 ~ 320

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!