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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.12
- 수록면
- 578 - 584 (7page)
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Purpose: Excess intake of sodium is a major diet-related risk factor for human diseases including hypertension and cancer as well as obesity and inflammation. However, findings are still controversial, and evidence is lacking in Koreans. Therefore, for better understanding of the role of dietary sodium intake in disease etiology, this study investigated the effects of dietary sodium intake on adiposity, inflammation, and hormones in Koreans. Methods: A total of 80 males and females joined the study. The general characteristics and dietary intake data were investigated by trained interviewers using a questionnaire and 24-h dietary recall, respectively. For the markers of adiposity, body weight, body mass index, percent of body fat, visceral fat area, and waist and hip circumference were measured. For the inflammation and hormone markers, leptin, adiponectin, insulin, tumor necrosis factor-α, and interleukin-6 were also analyzed. Results: Multivariate linear regression analyses suggested that dietary sodium intake was not associated with adiposity. However, dietary sodium showed a significant association with insulin level: Plasma insulin concentration increased with sodium intake independent of other dietary intake or percent of body fat (β= 0.296, adjusted r² = 0.276, p < 0.01). Other markers for inflammation and hormonal responses were not associated with dietary sodium intake. Conclusion: Findings suggested that dietary sodium intake may be a critical modifying factor in the level of plasma insulin. However, it showed a limited effect on obesity and other inflammation markers and hormone levels. These findings should be confirmed in larger, well-designed investigations.
목차
ABSTRACT
Introduction
Material and Methods
Results
Discussion
Summary
References
참고문헌 (29)
참고문헌 신청
Stamler J, Cohen J, Culter JA, Grandits G, Kjeldsberg M, Kuller L. Sodium intake and mortality from myocardial infarction: multiple risk factor intervention trial (MRFIT). Can J Cardiol 1997; 13 (Suppl B): 272B.
World Health Organization. Guideline: sodium intake for adults and children. Geneva: World Health Organization; 2012.
Asaria P, Chisholm D, Mathers C, Ezzati M, Beaglehole R. Chronic disease prevention: health effects and financial costs of strategies to reduce salt intake and control tobacco use. Lancet 2007; 370(9604): 2044-2053.
Bibbins-Domingo K, Chertow GM, Coxson PG, Moran A, Lightwood JM, Pletcher MJ, Goldman L. Projected effect of dietary salt reductions on future cardiovascular disease. N Engl J Med 2010; 362(7): 590-599.
Woo HD, Park S, Oh K, Kim HJ, Shin HR, Moon HK, Kim J. Diet and cancer risk in the Korean population: a metaanalysis. Asian Pac J Cancer Prev 2014; 15(19): 8509-8519.
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