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논문 기본 정보

자료유형
학술저널
저자정보
Taeg Kyun Shin (Chungnam National University) Samiru Sudharaka Wickramasuriya (Chungnam National University) Hyun Min Cho (Chungnam National University) Eunjoo Kim (Chungnam National University) Younghwa Kim (RDA) Juncheol Park (RDA) Shemil Priyan Macelline (Chungnam National University) Jung Min Heo (Chungnam National University) Young-Joo Yi (Chonbuk National University)
저널정보
충남대학교 농업과학연구소 Korean Journal of Agricultural Science Korean Journal of Agricultural Science Vol.44 No.4
발행연도
2017.12
수록면
477 - 486 (10page)

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This review provides an overview of dietary nucleotides as an alternative to in-feed antibiotics for weaning pigs. Dietary nucleotides are composed of DNA or RNA molecules and are normally contained in protein-rich feed ingredient, brewer’s yeast, yeast extract, and milk. Weaning pigs are suffering from several stresses, such as environmental challenges (i.e. crowding, transportation, and feeding). Such stressors can damage the intestinal epithelium and cause an invasion by Escherichia coli, secondary inflammatory responses, and post weaning diarrhea. To overcome weaning disorder, people often use antibiotics which reduce symptoms and boost growth performance. However, since antibiotics were banned due to concerns of antibiotic resistant bacteria, researchers are studying alternative materials to antibiotics. Dietary nucleotides are one of the alternative materials for replacing antibiotics and can be used in abnormal conditions, such as weaning diarrhea, low digestibility, and disease condition. Nucleotides have substances that have important roles in cell division and cell growth, affecting growth performance, intestinal condition, and immunological effect at the weaning stage. However, nucleotides’ composition is very different between sources and this aspect makes it difficult to utilize nucleotides at the weaning stage. Therefore, this review paper focuses on i) the characteristics and functions of dietary nucleotides and ii) the effect of dietary nucleotides on the growth performance and immune system of pigs.

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Abstract
Introduction
Nutritional management of newly-weaned pigs
Biochemical characteristic of nucleotides
Source of dietary nucleotides
Feeding value of dietary nucleotides
Growth and intestinal effect
Immunological effect
Conclusion
References

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UCI(KEPA) : I410-ECN-0101-2018-520-001702081