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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 701 - 709 (9page)
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초록· 키워드
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Objective This study investigated the proposed association between restless legs syndrome (RLS) and the prevalence of hypertension. Methods A meta-analysis was conducted based on searches of the PUBMED, EMBASE, Cochrane Library, and Korean electronic databases. Cohort and cross-sectional studies reporting the incidence of hypertension in individuals with RLS were included. Dichotomous data were pooled to obtain an odds ratio (OR) and 95% confidence interval (CI) for the prevalence of hypertension in individuals with RLS. The main outcome measure of the study was prevalence of hypertension in patients with RLS compared with a control group. Results One cohort study and eight cross-sectional studies were included in the meta-analysis. Individuals with RLS had an increased prevalence of hypertension (all studies: OR=1.13, 95% CI=1.04–1.23; cross-sectional studies: OR=1.12, 95% CI=1.01–1.24). However, in subgroup analyses controlling for cardiovascular risk factors, such as diabetes mellitus and dyslipidemia, the differences in the prevalence of hypertension between RLS and control patients were no longer significant. Conclusion Patients with RLS may have a higher prevalence of hypertension, according to a pooled analysis, but the results remain to be confirmed in well-designed prospective studies.
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참고문헌 (47)
참고문헌 신청
Allen RP / 2005 / Restless legs syndrome prevalence and impact: REST general population study / Arch Intern Med 165:1286~1292
Tison F / 2005 / Epidemiology of restless legs syndrome in French adults: a nationwide survey: the INSTANT Study / Neurology 65:239~246
Sevim S / 2004 / Correlation of anxiety and depression symptoms in patients with restless legs syndrome: a population based survey / J Neurol Neurosurg Psychiatry 75:226~230
Allen RP / 2017 / Restless Legs Syndrome and Periodic Limb Movements during Sleep A2 - Kryger, Meir;Principles and Practice of Sleep Medicine (Sixth Edition) / Elsevier :923~934
Trenkwalder C / 2016 / Restless legs syndrome associated with major diseases: a systematic review and new concept / Neurology 86:1336~1343
Tison F / 2005 / Epidemiology of restless legs syndrome in French adults: a nationwide survey: the INSTANT Study / Neurology 65:239~246
Sevim S / 2004 / Correlation of anxiety and depression symptoms in patients with restless legs syndrome: a population based survey / J Neurol Neurosurg Psychiatry 75:226~230
Allen RP / 2017 / Restless Legs Syndrome and Periodic Limb Movements during Sleep A2 - Kryger, Meir;Principles and Practice of Sleep Medicine (Sixth Edition) / Elsevier :923~934
Trenkwalder C / 2016 / Restless legs syndrome associated with major diseases: a systematic review and new concept / Neurology 86:1336~1343
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