지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 306 - 312 (7page)
이용수
초록· 키워드
오류제보하기
Objective To investigate the relationship between serum creatine kinase (CK) level and pulmonary function in Duchenne muscular dystrophy (DMD).
Methods A total of 202 patients with DMD admitted to the Department of Rehabilitation Medicine, Gangnam Severance Hospital were enrolled from January 1, 1999 to March 31, 2015. Seventeen patients were excluded. Data collected from the 185 patients included age, height, weight, body mass index, pulmonary function tests including forced vital capacity (FVC), peak cough flow, maximal expiratory pressure (MEP), and maximal inspiratory pressure (MIP), and laboratory measurements (serum level of CK, CK-MB, troponin-T, and B-type natriuretic peptide). FVC, MEP, and MIP were expressed as percentages of predicted normal values.
Results Serum CK activities were elevated above normal levels, even in the oldest DMD group. Serum CK level was strongly correlated with pulmonary functions of sitting FVC (p<0.001), supine FVC (p<0.001), MIP (p=0.004), and MEP (p<0.001).
Conclusion Serum CK level is a reliable screening test even in patients with advanced DMD, and is a strong predictor of pulmonary functions.
목차
등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
Bushby K / 2014 / Ataluren treatment of patients with nonsense mutation dystrophinopathy / Muscle Nerve 50 : 477 ~ 487
Deconinck N / 2007 / Pathophysiology of Duchenne muscular dystrophy: current hypotheses / Pediatr Neurol 36 : 1 ~ 7
Finkel RS / 2013 / Phase 2a study of ataluren-mediated dystrophin production in patients with nonsense mutation Duchenne muscular dystrophy / PLoS One 8 : e81302 ~
Haas M / 2015 / European Medicines Agency review of ataluren for the treatment of ambulant patients aged 5 years and older with Duchenne muscular dystrophy resulting from a
Hahn A / 1997 / Clinical implications of maximal respiratory pressure determinations for individuals with Duchenne muscular dystrophy / Arch Phys Med Rehabil 78 : 1 ~ 6
Deconinck N / 2007 / Pathophysiology of Duchenne muscular dystrophy: current hypotheses / Pediatr Neurol 36 : 1 ~ 7
Finkel RS / 2013 / Phase 2a study of ataluren-mediated dystrophin production in patients with nonsense mutation Duchenne muscular dystrophy / PLoS One 8 : e81302 ~
Haas M / 2015 / European Medicines Agency review of ataluren for the treatment of ambulant patients aged 5 years and older with Duchenne muscular dystrophy resulting from a
Hahn A / 1997 / Clinical implications of maximal respiratory pressure determinations for individuals with Duchenne muscular dystrophy / Arch Phys Med Rehabil 78 : 1 ~ 6
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Analysis of Pulmonary Function Test in Korean Patients With Duchenne Muscular Dystrophy: Comparison of Foreign and Korean Reference Data
Annals of Rehabilitation Medicine
2016 .01
-
Comparison of Pulmonary Functions at Onset of Ventilatory Insufficiency in Patients With Amyotrophic Lateral Sclerosis, Duchenne Muscular Dystrophy, and Myotonic Muscular Dystrophy
Annals of Rehabilitation Medicine
2016 .01
-
뒤시엔느 근디스트로피 환자의 혈청 아미노전이효소의 예측치
대한근전도 전기진단의학회지
2015 .01
-
Duchenne Muscular Dystrophy: A Case Report and Literature
Cardiovascular Imaging Asia
2023 .01
-
Identification of two novel Duchenne muscular dystrophies mutations in patients with Becker muscular dystrophy
Journal of genetic medicine
2017 .01
-
Creatine Kinase (CK)-MB-to-Total-CK Ratio: a Laboratory Indicator for Primary Cancer Screening
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Defining the Normal Trends of Serum Creatine Kinase Levels Following Spinal Surgery
Asian Spine Journal
2019 .01
-
진동 자극 유무에 따른 호흡 저항 훈련 시 폐 기능과 호흡근의 즉각적인 차이가 있을까?
대한물리치료과학회지
2018 .01
-
정상 성인에서 Vitamin D 결핍과 폐기능과의 연관성에 관한 연구
Allergy Asthma & Respiratory Diseases
2015 .01
-
Magnetic Resonance Imaging as a Biomarker for Duchenne Muscular Dystrophy
한국전문물리치료학회지
2015 .01
-
Early Marker of Myocardial Deformation in Children with Duchenne Muscular Dystrophy Assessed Using Echocardiographic Myocardial Strain Analysis
Yonsei Medical Journal
2016 .01
-
Dental management of patient with Duchenne Muscular Dystrophy under general anesthesia in a child: A case report
International Journal of Disability and Oral Health
2020 .06
-
Cardiac and Pulmonary Management Status of Duchenne Muscular Dystrophy in South Korea Based on Data From the National Health Insurance Database
Journal of Clinical Neurology
2022 .09
-
Generation and use of dystrophin-mutant mice for developing genetic strategies treating Duchenne muscular dystrophy (DMD)
한국실험동물학회 학술발표대회 논문집
2018 .01
-
Maximal Inspiratory Pressure and Maximal Expiratory Pressure in Healthy Korean Children
Annals of Rehabilitation Medicine
2017 .01
-
Elevation of serum creatine kinase during methimazole treatment of Graves disease in a 13-year-old girl and a literature review of similar cases
Annals of Pediatirc Endocrinology & Metabolism
2015 .01
-
중환자에서 Creatine Kinase 상승의 임상적 의미
Journal of Acute Care Surgery
2018 .01
-
Cytokeratin 15 is an Effective Indicator for Progression and Malignancy of Esophageal Squamous Cell Carcinomas
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Cardiac function associated with home ventilator care in Duchenne muscular dystrophy
Clinical and Experimental Pediatrics
2018 .01
-
Clinical Implications of Routine Monitoring of Pulmonary Function and Ventilation in Patients with Duchenne Muscular Dystrophy
Yonsei Medical Journal
2022 .06
이 논문의 저자 정보
최근 본 자료
댓글(0)
0