지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 28 - 34 (7page)
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초록· 키워드
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Background: Pregnancy induces dramatic cardiovascular changes in order to meet the increasing metabolic needs. Adaptive change of left ventricle (LV) might be modified in pregnancy complicated by hypertension.
Methods: Data from 193 consecutive pregnant women were analyzed. Clinical and echocardiographic data were compared in normotensive and hypertensive women.
Results: Significantly higher LV mass indexed by height was observed in hypertensive women compared with normotensive women (84 ± 21 g/m vs. 97 ± 20 g/m, p = 0.001). Diastolic function measured by the ratio of peak velocity of early diastolic transmitral blood flow to early diastolic mitral annular velocity was impaired in hypertensive women (11.0 ± 3.0 vs. 9.2 ± 2.5, p < 0.001). Such change was more prominent in women with gestational hypertension (GH) than those with chronic hypertension (CH). Heavy maternal weight was an independent factor associated with LV hypertrophy (LVH) in both normotensive and hypertensive women. Overt eccentric LVH was more frequent than concentric remodeling/hypertrophy (24% vs. 8.4%) in GH, while the opposite result was observed in CH (14% vs. 23%).
Conclusion: Hypertensive pregnancy is associated with significant LVH and diastolic dysfunction. CH seems to induce different LV remodeling pattern from GH. Heavy maternal weight during pregnancy might intensify the unfavorable remodeling of LV, particularly in hypertensive pregnancy.
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참고문헌 (18)
참고문헌 신청
Warnes CA / 2014 / Braunwald’s heart disease: a textbook of cardiovascular medicine / Elsevier Saunders :1755~1770
Regitz-Zagrosek V / 2011 / ESC Guidelines on the management of cardiovascular diseases during pregnancy:the Task Force on the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC) / Eur Heart J 32:3147~3197
Geva T / 1997 / Effects of physiologic load of pregnancy on left ventricular contractility and remodeling / Am Heart J 133:53~59
Lang RM / 2005 / Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology / J Am Soc Echocardiogr 18:1440~1463
Nagueh SF / 2009 / Recommendations for the evaluation of left ventricular diastolic function by echocardiography / J Am Soc Echocardiogr 22:107~133
Regitz-Zagrosek V / 2011 / ESC Guidelines on the management of cardiovascular diseases during pregnancy:the Task Force on the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC) / Eur Heart J 32:3147~3197
Geva T / 1997 / Effects of physiologic load of pregnancy on left ventricular contractility and remodeling / Am Heart J 133:53~59
Lang RM / 2005 / Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology / J Am Soc Echocardiogr 18:1440~1463
Nagueh SF / 2009 / Recommendations for the evaluation of left ventricular diastolic function by echocardiography / J Am Soc Echocardiogr 22:107~133
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