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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 187 - 192 (6page)
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초록· 키워드
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In this report, fifteen monoclonal antibodies (MAbs) against an avian influenza virus (H9N2 subtype) were newly produced and characterized. These MAbs proved to react to the epitopes of nucleocapsid protein (NP), hemagglutinin (HA), neuraminidase (NA) and non-structural protein 1 (NS1) of Korean H9N2 strain, respectively. Two HA-specific MAbs showed the ability to inhibit the hemagglutination activity of H9N2 subtype avian influenza virus when tested by hemagglutination inhibition (HI) assay.
All MAbs did not cross-react with other avian-origin viruses (Newcastle disease virus, infectious bursal disease virus, infectious bronchitis virus and avian rotavirus) by immunofluorescence test or enzyme- linked immunosorbent assay. The MAbs produced in this study could be useful as the materials for diagnostics and therapeutics against Korean-lineage H9N2 virus infections.
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등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Aymard-Henry M / 1973 / Influenza virus neuraminidase and neuraminidase-inhibition test procedures / Bull World Health Organ 48 : 199 ~
Bright RA / 2005 / Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern / Lancet 366 : 1175 ~ 1181
Butt K / 2005 / Human infection with an avian H9N2 influenza A virus in Hong Kong in 2003 / J Clin Microbiol 43 : 5760 ~ 5767
Carrat F / 2007 / Influenza vaccine: the challenge of antigenic drift / Vaccine 25 : 6852 ~ 6862
Chen R / 2006 / Avian influenza virus exhibits rapid evolutionary dynamics / Mol Biol Evol 23 : 2336 ~ 2341
Bright RA / 2005 / Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern / Lancet 366 : 1175 ~ 1181
Butt K / 2005 / Human infection with an avian H9N2 influenza A virus in Hong Kong in 2003 / J Clin Microbiol 43 : 5760 ~ 5767
Carrat F / 2007 / Influenza vaccine: the challenge of antigenic drift / Vaccine 25 : 6852 ~ 6862
Chen R / 2006 / Avian influenza virus exhibits rapid evolutionary dynamics / Mol Biol Evol 23 : 2336 ~ 2341
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