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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 81 - 88 (8page)
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Purpose: 18^F-fluorodeoxyglucose positron emission tomography/computed tomography (18^F-FDG PET/CT) scans are frequently performed for the screening or staging of malignant tumors. This study aimed to assess the usefulness of 18^F-FDG PET/CT in detection of gastric cancer recurrence after curative gastrectomy. Materials and Methods: Eighty nine patients who had undergone curative gastrectomy due to gastric cancer and had 18^F-FDG PET/CT and contrast CT scans within 2 weeks for surveillance in asymptomatic patients (n = 11) or to clarify suspected recurrence (n = 78) were consecutively collected and retrospectively analyzed. They had clinical follow-up for at least 12 months after PET/CT and CT scans. Results: Fifteen of the 89 patients (16.9%) were diagnosed with recurrent gastric cancer in 21 organs. Forty one organs showed an increase in FDG uptake, and only 9 of these organs were diagnosed with recurrent gastric cancer by 18^F-FDG PET/CT. The sensitivity,specificity, positive predictive value, negative predictive value, and diagnostic accuracy of the 18F-FDG PET/CT were 42.9%, 59.7%, 29.3%, 78.2%, and 57.3%, respectively. On the CT scan, 18 of 21 recurrent gastric cancers were detected,and 7 cases were in agreement with the 18^F-FDG PET/CT. The sensitivity and specificity of the CT scan were 85.8% and 87.3%, respectively, which are superior to the 18^F-FDG PET/CT. When we diagnosed a recurrence based on either 18^F-FDG PET/CT or CT scans, the sensitivity increased to 95.2% and the specificity decreased to 45.6%, when compared with the contrast CT scan alone. Conclusion: 18^F-FDG PET/CT is an insufficient diagnostic method in detection of recurrence after curative gastrectomy, and even less accurate than contrast CT scan alone.
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참고문헌 (17)
참고문헌 신청
Beatty JS / 2009 / Incidental PET/CT findings in the cancer patient: how should they be managed / Surgery 146 : 274 ~ 281
De Potter T / 2002 / Whole-body PET with FDG for the diagnosis of recurrent gastric cancer / Eur J Nucl Med Mol Imaging 29 : 525 ~ 529
Habermann CR / 2004 / Preoperative staging of gastric adenocarcinoma: comparison of helical CT and endoscopic US / Radiology 230 : 465 ~ 471
Halvorsen RA Jr / 1996 / Diagnosis and staging of gastric cancer / Semin Oncol 23 : 325 ~ 335
Ishimori T / 2005 / Detection of unexpected additional primary malignancies with PET/CT / J Nucl Med 46 : 752 ~ 757
De Potter T / 2002 / Whole-body PET with FDG for the diagnosis of recurrent gastric cancer / Eur J Nucl Med Mol Imaging 29 : 525 ~ 529
Habermann CR / 2004 / Preoperative staging of gastric adenocarcinoma: comparison of helical CT and endoscopic US / Radiology 230 : 465 ~ 471
Halvorsen RA Jr / 1996 / Diagnosis and staging of gastric cancer / Semin Oncol 23 : 325 ~ 335
Ishimori T / 2005 / Detection of unexpected additional primary malignancies with PET/CT / J Nucl Med 46 : 752 ~ 757
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