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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 105 - 111 (7page)
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Purpose: To investigate and compare the clinical manifestation and prognosis of preterm and full-term infants with Down syndrome (DS).
Methods: We retrospectively reviewed 80 patients diagnosed with DS and confirmed by chromosomal study at the Samsung Medical Center between January 1994 and July 2014. Data on demographic characteristics, associated anomalies, treatment, prognosis and cause of death were compared between preterm and full-term DS infants.
Results: Of the 80 confirmed DS patients, there were 49 (61%) full-term and 31 (38%) preterm DS infants. The mean gestational age of full-term DS infants was 38+1±0+2 weeks (range, 37+0-40+0 weeks) and the mean birth weight was 3,007±418 g (range, 1,930-4,100 g). The mean gestational age of preterm infants was 34+1±2+1 weeks (range, 29+1-36+6 weeks) and the mean birth weight was 2,181±598 g (range, 890-3,500 g). There were no differences in demographics, associated anomalies, mortality or related factors, or the rate of active treatment between full-term and preterm DS infants.
Conclusion: In this single center study, the mortality rate of preterm DS infants was comparable to that of full-term DS infants. Larger national cohort studies might be needed to further investigate the prognosis of preterm DS infants.
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참고문헌 (17)
참고문헌 신청
Alleman BW / 2013 / Individual and center-level factors affecting mortality among extremely low birth weight infants / Pediatrics 132 : e175 ~ 184
Bae CW / 1996 / Neonatal statistics of Korea in 1996: collective results of livebirths, neonatal mortality, and incidence of discharge against medical advice at 64 hospitals
Boghossian NS / 2014 / Mortality and morbidity of VLBW infants with trisomy 13 or trisomy 18 / Pediatrics 133 : 226 ~ 235
Corina N. Schoen / 2015 / Why the United States preterm birth rate is declining / American Journal of Obstetrics and Gynecology 213 (2) : 175 ~ 180
Day SM / 2005 / Mortality and causes of death in persons with Down syndrome in California / Dev Med Child Neurol 47 : 171 ~ 176
Bae CW / 1996 / Neonatal statistics of Korea in 1996: collective results of livebirths, neonatal mortality, and incidence of discharge against medical advice at 64 hospitals
Boghossian NS / 2014 / Mortality and morbidity of VLBW infants with trisomy 13 or trisomy 18 / Pediatrics 133 : 226 ~ 235
Corina N. Schoen / 2015 / Why the United States preterm birth rate is declining / American Journal of Obstetrics and Gynecology 213 (2) : 175 ~ 180
Day SM / 2005 / Mortality and causes of death in persons with Down syndrome in California / Dev Med Child Neurol 47 : 171 ~ 176
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