지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제25권 제10호
- 발행연도
- 2015.1
- 수록면
- 1,680 - 1,686 (7page)
이용수
초록· 키워드
오류제보하기
Inhibition of 4-nitroquinoline-1-oxide (4-NQO) genotoxicity by a probiotic strain of Lactobacillus rhamnosus (IMC501) was assessed by the prokaryotic short-term bioassay SOSChromotest, using Escherichia coli PQ37 as the target organism. Results showed the ability of strain IMC501 to rapidly and markedly counteract, in vitro, the DNA damage originated by the considered genotoxin. The inhibition was associated with a spectroscopic hypsochromic shift of the original 4-NQO profile and progressive absorbance increase of a new peak. IR-Raman and GC-MS analyses confirmed the disappearance of 4-NQO after contact with the microorganism, showing also the absence of any genotoxic molecule potentially available for metabolic activation (i.e., 4-hydroxyaminoquinoline-1-oxide and 4-nitrosoquinoline-1-oxide). Furthermore, we have shown the presence of the phenyl-quinoline and its isomers as major non-genotoxic conversion products, which led to the hypothesis of a possible pattern of molecular transformation. These findings increase knowledge on lactobacilli physiology and contribute to the further consideration of antigenotoxicity as a nonconventional functional property of particular probiotic strains.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Ambalam P / 2011 / In vitro mutagen binding and antimutagenic activity of human Lactobacillus rhamnosus 231 / Anaerobe 17 : 217 ~ 222
Benson AM / 1993 / Conversion of 4-nitroquinoline 1-oxide (4-NQO) to 4-hydroxyaminoquinoline 1-oxide by a dicumarolresistant hepatic 4NQO nitroreductase in rats and mice / Bi
Bond TJ / 1970 / Characteristics of growth inhibition of Lactobacillus casei by 4-nitroquinoline-N-oxide / Appl. Microbiol 20 : 536 ~ 538
Caldini G / 2002 / Inhibition of 4-nitroquinoline-1-oxide genotoxicity by Bacillus strains / Res. Microbiol 153 : 165 ~ 171
Caldini G / 2005 / Screening of potential lactobacilli antigenotoxicity by microbial and mammalian cell-based tests / Int. J. Food Microbiol 102 : 37 ~ 47
Benson AM / 1993 / Conversion of 4-nitroquinoline 1-oxide (4-NQO) to 4-hydroxyaminoquinoline 1-oxide by a dicumarolresistant hepatic 4NQO nitroreductase in rats and mice / Bi
Bond TJ / 1970 / Characteristics of growth inhibition of Lactobacillus casei by 4-nitroquinoline-N-oxide / Appl. Microbiol 20 : 536 ~ 538
Caldini G / 2002 / Inhibition of 4-nitroquinoline-1-oxide genotoxicity by Bacillus strains / Res. Microbiol 153 : 165 ~ 171
Caldini G / 2005 / Screening of potential lactobacilli antigenotoxicity by microbial and mammalian cell-based tests / Int. J. Food Microbiol 102 : 37 ~ 47
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Dysbiosis of Oral Microbiota in a Mouse Model of Head and Neck Cancer Induced by 4-Nitroquinoline 1-Oxide
한국미생물학회 학술대회논문집
2022 .10
-
Dysbiosis of Oral Microbiota in a Mouse Model of Head and Neck Cancer Induced by 4-Nitroquinoline 1-Oxide
한국미생물학회 학술대회논문집
2021 .08
-
Comparative Genomic Analysis of Four Probiotic Lactobacillus Species, L. acidophilus, L. helveticus, L. rhamnosus, and L. casei
한국미생물학회 학술대회논문집
2020 .10
-
Comparative Genomic Analysis of Four Probiotic Lactobacillus Species, L. acidophilus, L. helveticus, L. rhamnosus, and L. casei
한국미생물학회 학술대회논문집
2019 .04
-
NQO1 (NAD(P)H:quinone oxidoreductase 1)에 의한 대식세포 활성화 억제
생명과학회지
2017 .08
-
Lactobacillus paracasei와 Lactobacillus rhamnosus를 이용한 요구르트의 효모 성장 억제와 품질 향상 효과
생명과학회지
2016 .12
-
Trends, Functionalities, and Prospects of Probiotics
한국미생물·생명공학회지
2022 .12
-
Characterization of Lactobacillus salivarius Strain Isolated from Piglet Feces for Probiotic Uses
한국미생물학회 학술대회논문집
2016 .04
-
Whole-Cell Biocatalysis for Producing Ginsenoside Rd from Rb1 Using Lactobacillus rhamnosus GG
Journal of Microbiology and Biotechnology
2016 .01
-
Immunomodulatory effects of seven viable and sonicated Lactobacillus spp. and anti-bacterial activities of L. rhamnosus and L. helvetilus
미생물학회지
2019 .12
-
Comparative Genomic Analysis of Lactobacillus rhamnosus BFE5264, a Probiotic Strain Isolated from Traditional Maasai Fermented Milk
한국미생물·생명공학회지
2019 .01
-
Anti-inflammatory Effects of Lactobacillus fermentum PL9988 and Its Characteristics as Probiotics
한국미생물학회 학술대회논문집
2021 .08
-
The Effect of Milk Protein on the Biological and Rheological Properties of Probiotic Capsules
Journal of Microbiology and Biotechnology
2020 .01
-
Pan-genomic Analysis of Lactobacillus salivarius Strains as Anti-pathogenic Swine Probiotics
한국미생물학회 학술대회논문집
2016 .04
-
Metabolic Regulation of Longevity and Immune Response in Caenorhabditis elegans by Ingestion of Lacticaseibacillus rhamnosus IDCC 3201 Using Multi-Omics Analysis
Journal of Microbiology and Biotechnology
2024 .05
-
Complete genome sequence of a potential probiotic Lacticaseibacillus rhamnosus strain LDTM 7511, isolated from Korean infant feces
미생물학회지
2022 .06
-
Evaluation of the Probiotic Potential of Microorganisms Isolated from the Intestinal Tract of Cultured Epinephelus akaara
한국미생물·생명공학회지
2024 .03
-
Identification of Probiotic Strains with Anti-Tuberculosis Activity and Their Characterization as Potential Therapeutic Agents
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2024 .12
-
The Functional Roles of Lactobacillus acidophilus in Different Physiological and Pathological Processes
Journal of Microbiology and Biotechnology
2022 .10
-
Complete genome sequence of probiotic Lactobacillus plantarum IDCC3501 isolated from kimchi
미생물학회지
2019 .12
이 논문의 저자 정보
최근 본 자료
댓글(0)
0