지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 161 - 171 (11page)
이용수
초록· 키워드
오류제보하기
Introduction: This study was to assess the effectiveness of new bone formation and regeneration by using a rhBMP-2 and β-TCP as a carrier in rabbits’mandible.
Materials and Methods: The mandibles of 36 rabbits were exposed and cortical bone was penetrated for this study. The experimental subjects were divided into 3 groups each 12 rabbits ; control group, experimental group 1, and experimental group 2. Control group had the defect itself without any treatment, in the experimental group 1, β-TCP only was grafted, and in the experimental group 2, rhBMP-2 soaked in β-TCP was grafted.
The rabbits were sacrificed after 1, 2, 3, 4, 6, and 8weeks, and new bone formation area was examined and measured for bone quantitative and qualitative analysis with light, fluorescent and polarized microscopy.
Results: In the experimental group 1, new bone formation from the adjacent host bone was made by osteoconduction, and in the experimental group 2, direct new bone formation by osteoinduction of rhBMP-2 as well as new bone formation by osteoconduction of β-TCP were observed.
Conclusion: rhBMP-2 of experimental group 2 is very effective in the bone formation in early 2weeks and bone remodelling from 3weeks.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Aldinger G / 1991 / Bone morphogenetic protein: a review / Int Orthop 15 : 169 ~ 177
Barboza EP / 2000 / Ridge augmentation following implantation of recombinant human bone morphogenetic protein-2 in the dog / J Periodontol 71 : 488 ~ 496
Bessho K / 1999 / BMP stimulation of bone response adjacent to titanium implants in vivo / Clin Oral Implants Res 10 : 212 ~ 218
Dunn CA / 2005 / Franceschi RT, Bruce Rutherford R, Giannobile WV. BMP gene delivery for alveolar bone engineering at dental implants defects / Mol Ther 11 : 294 ~ 299
Geiger M / 2003 / Collagen sponges for bone regeneration with rhBMP-2 / Adv Drug Deliv Rev 55 : 1613 ~ 1629
Barboza EP / 2000 / Ridge augmentation following implantation of recombinant human bone morphogenetic protein-2 in the dog / J Periodontol 71 : 488 ~ 496
Bessho K / 1999 / BMP stimulation of bone response adjacent to titanium implants in vivo / Clin Oral Implants Res 10 : 212 ~ 218
Dunn CA / 2005 / Franceschi RT, Bruce Rutherford R, Giannobile WV. BMP gene delivery for alveolar bone engineering at dental implants defects / Mol Ther 11 : 294 ~ 299
Geiger M / 2003 / Collagen sponges for bone regeneration with rhBMP-2 / Adv Drug Deliv Rev 55 : 1613 ~ 1629
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
The BMPs expression and histomorphometric study of β-TCP / rhBMP-2 Grafting on the rabbit cranial bone defects
대한구강악안면외과학회지
2008 .01
-
재조합 제2형 인간골형성단백질이 코팅된 삼인산칼슘을 이용한 발치창 보존술: 3개월간의 무작위 전향적 임상연구
Oral Biology Research
2011 .01
-
rhBMP-2의 작용기전과 구강악안면 영역의 골재생을 위한 rhBMP-2의 활용
대한치과의사협회지
2015 .01
-
골형성유도단백질(rhBMP-2)을 이용한 치조골 결손부의 골이식술
대한치과의사협회지
2015 .01
-
백서 두개골 결손에서 rhBMP-2와 다양한 carrier의 골재생 유도효과
Journal of Periodontal & Implant Science
2008 .01
-
가토 두개골에서 β-TCP와 자가골 이식에 관한 실험적 연구
대한구강악안면외과학회지
2004 .01
-
Effects of micro-porosity and local BMP-2 administration on bioresorption of β-TCP and new bone formation
생체재료학회지
2019 .01
-
Bone formation with alloplastic graft substitutes in critical-sized rat calvarial defects
Oral Biology Research
2011 .01
-
The efficacy of rhBMP-2 loaded hydrogel composite on bone formation around dental implants in mandible bone defects of minipigs
생체재료학회지
2020 .01
-
가토 상악동에 이식된 β-TCP의 골치유에 관한 실험적 연구
대한구강악안면외과학회지
2006 .01
-
RP titanium cap과 rhBMP-2를 이용하여 형성된 신생골의 미세전산화단층촬영을 이용한 평가
대한구강악안면외과학회지
2010 .01
-
골수유래줄기세포에서 분화된 골유사세포에서 β-TCP와 rhBMP-2의 골형성 효과에 관한 연구
대한구강악안면외과학회지
2008 .01
-
rhBMP-2가 저칼슘식이 투여 백서의 골결손부 치유에 미치는 영향
대한구강악안면방사선학회지
2004 .01
-
Evaluation of bone formation after grafting with cancellous and cortical bone allografts in the treatment of bone defects around implants
Oral Biology Research
2011 .01
-
백서두개골 결손부에서 Escherichia coli 발현 시스템으로 생산된 rhBMP-2의 골형성 효과
Journal of Periodontal & Implant Science
2009 .01
-
Demineralized dentin matrix combined with recombinant human bone morphogenetic protein-2 in rabbit calvarial defects
대한구강악안면외과학회지
2016 .01
-
Recombinant human bone morphogenetic protein-2와 anorganic bovine bone 혼합이식 후치유과정에 관한 실험적 연구
Oral Biology Research
2014 .01
-
Effects of Escherichia Coli-derived Recombinant Human Bone Morphogenetic Protein-2 Loaded Porous Hydroxyaptite-based Ceramics on Calvarial Defect in Rabbits
대한골대사학회지
2017 .01
-
rhBMP-2 using biphasic calcium phosphate block as a carrier induces new bone formation in a rat subcutaneous tissue
Journal of Periodontal & Implant Science
2008 .01
-
Sinus augmentation using rhBMP-2-loaded synthetic bone substitute with simultaneous implant placement in rabbits
Journal of Periodontal & Implant Science
2017 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0