지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 169 - 173 (5page)
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초록· 키워드
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Purpose: Agenesis of the septum pellucidum (ASP) is a very rare disease that can be isolated or associated with other brain abnormalities. The neurological prognosis of isolated ASP remains controversial. The aim of this study was to evaluate the clinical outcome of neonates with ASP. Methods: We retrospectively analyzed the medical records of 12 neonates with isolated ASP or ASP combined with other brain abnormalities who were born at Cheil General Hospital & Women's Healthcare Center between January 2007 and December 2017. Results: Of the 12 neonates, six were identified prenatally and six were identified postnatally. Isolated ASP was found in eight neonates; of these, four were detected antenatally. ASP associated with other brain abnormalities was found in four neonates. ASP was complete in nine neonates, including six with isolated ASP, and partial in three, including two with isolated ASP. Six of the eight neonates with isolated ASP had normal neurological development, except two who were lost to follow-up. Among the four neonates with other associated brain abnormalities, two had delayed motor development and a seizure, one had normal development, and one was lost to follow-up. In all neonates, ophthalmological examination revealed no optic nerve abnormalities. Conclusion: Isolated ASP seems to have a good neurological prognosis without ocular problems. This result needs to be confirmed by larger prospective studies over a longer developmental timeline.
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등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Barkovich AJ / 1989 / Absence of the septum pellucidum: a useful sign in the diagnosis of congenital brain malformations / AJR Am J Roentgenol 152:353~360
Sarwar M. / 1989 / The septum pellucidum: normal and abnormal / AJNR Am J Neuroradiol 10:989~1005
Schaefer GB / 1994 / Subtle anomalies of the septum pellucidum and neurodevelopmental deficits / Dev Med Child Neurol 36:554~559
Malinger G / 2005 / Differential diagnosis in fetuses with absent septum pellucidum. Ultrasound Obstet / Ultrasound Obstet Gynecol 25:42~49
Damaj L / 2010 / Pediatric outcome of children with the prenatal diagnosis of isolated septal agenesis / Prenat Diagn 30:1143~1150
Sarwar M. / 1989 / The septum pellucidum: normal and abnormal / AJNR Am J Neuroradiol 10:989~1005
Schaefer GB / 1994 / Subtle anomalies of the septum pellucidum and neurodevelopmental deficits / Dev Med Child Neurol 36:554~559
Malinger G / 2005 / Differential diagnosis in fetuses with absent septum pellucidum. Ultrasound Obstet / Ultrasound Obstet Gynecol 25:42~49
Damaj L / 2010 / Pediatric outcome of children with the prenatal diagnosis of isolated septal agenesis / Prenat Diagn 30:1143~1150
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