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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 224 - 232 (9page)
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초록· 키워드
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ObjectiveThis study was conducted to demonstrate the temporal trends in perinatal outcomes of triplet pregnancies over thelast two decades. MethodsThe medical records of patients with triplet pregnancies at two Korean tertiary-care hospitals from 1992 to 2012 wereretrospectively reviewed in regard to maternal and neonatal outcomes. The study was divided into two periods foranalysis: period I (1992–2001) and period II (2003–2012). ResultsOver a 21-year period, 65 women with triplet pregnancies and 185 neonates were analyzed. Period II, whencompared with period I, was associated with improved maternal outcomes, characterized by a decreased incidenceof preeclampsia (31.8% vs. 2.3%, P=0.002) and anemia (68.2% vs. 30.2%, P=0.003) during pregnancy. Regardingneonatal aspects, the composite morbidity of period II was significantly decreased compared with that of period I,as assessed with a generalized estimating equation for logistic regression (26.2% vs. 8.1%, P=0.03). Multivariableanalysis revealed that the gestational age at delivery and the period were significantly associated with the compositeneonatal morbidity (P<0.001 and 0.007, respectively). ConclusionImproved neonatal morbidity was associated with a higher gestational age at delivery and with the more recentdecade.
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참고문헌 (36)
참고문헌 신청
Martin JA / 2011 / Births : final data for 2009 / Natl Vital Stat Rep 60:1~70
Black M / 2010 / Epidemiology of multiple pregnancy and the effect of assisted conception / Semin Fetal Neonatal Med 15:306~312
Ferraretti AP / 2012 / Assisted reproductive technology in Europe, 2008 : results generated from European registers by ESHRE / Hum Reprod 27:2571~2584
Hur YM / 2005 / Changes in twinning rates in South Korea : 1981-2002 / Twin Res Hum Genet 8:76~79
최영민 / 2013 / Current status of assisted reproductive technology in Korea, 2009 / Obstetrics & Gynecology Science 56(06):353~361
Black M / 2010 / Epidemiology of multiple pregnancy and the effect of assisted conception / Semin Fetal Neonatal Med 15:306~312
Ferraretti AP / 2012 / Assisted reproductive technology in Europe, 2008 : results generated from European registers by ESHRE / Hum Reprod 27:2571~2584
Hur YM / 2005 / Changes in twinning rates in South Korea : 1981-2002 / Twin Res Hum Genet 8:76~79
최영민 / 2013 / Current status of assisted reproductive technology in Korea, 2009 / Obstetrics & Gynecology Science 56(06):353~361
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