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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 452 - 459 (8page)
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Objective Little has been explored about a reflection towards self-image in schizophrenia, though it can be related to heterogeneous symptoms of the illness. We identified the neural basis of ambivalence towards ideal self-image in patients with schizophrenia. Methods 20 patients with schizophrenia and 20 healthy controls underwent functional MRI while the self-image reflection tasks of determining whether to agree with sentences describing their actual or ideal self-image that contained one of the adjective pairs with opposite valence. The interaction between the group and ideal ambivalence score was examined, and group differences in functional connectivity related to ambivalence towards ideal self-image were further studied. Results The interaction of group-by-ideal ambivalence score was shown in the dorsal anterior cingulate cortex and dorsolateral prefrontal cortex, where activities were positively correlated with the level of ideal self-image ambivalence in patients, but not in controls. Task-related decrease in functional connectivity was shown between the orbitofrontal cortex and cerebellum in patients. Conclusion The process of reflecting on ambivalent ideal self-image in schizophrenia may be related to aberrant prefrontal activity and connectivity. Abnormality in the prefrontal regions that take part in cognitive conflict monitoring and value judgment may underlie the pathophysiology of increased ambivalence towards ideal self-image.
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참고문헌 (48)
참고문헌 신청
Sass LA / 2003 / Schizophrenia, consciousness, and the self / Schizophr Bull 29:427~444
Moe AM / 2014 / Schizophrenia and the sense of self / Schizophr Bull 40:161~168
Tangney JP / 1998 / Are shame and guilt related to distinct self-discrepancies? A test of Higgins’s(1987)hypotheses / J Pers Soc Psychol 75:256~268
Higgins ET / 1987 / Self-discrepancy : a theory relating self and affect / Psychol Rev 94:319~340
Bhar SS / 2007 / An investigation of self-ambivalence in obsessivecompulsive disorder / Behav Res Ther 45:1845~1857
Moe AM / 2014 / Schizophrenia and the sense of self / Schizophr Bull 40:161~168
Tangney JP / 1998 / Are shame and guilt related to distinct self-discrepancies? A test of Higgins’s(1987)hypotheses / J Pers Soc Psychol 75:256~268
Higgins ET / 1987 / Self-discrepancy : a theory relating self and affect / Psychol Rev 94:319~340
Bhar SS / 2007 / An investigation of self-ambivalence in obsessivecompulsive disorder / Behav Res Ther 45:1845~1857
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