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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Background: There has been interest in the clinical potential of bone turnover markers (BTMs) as tools both for assessing fracture risk and for monitoring treatment. However, the practical use of BTMs has been limited by their biological variability and difficulties in the interpretation of results. We investigated the current situation of application of BTMs by clinicians in Korea for the management of osteoporosis through a survey asking the patterns of BTMs prescription in clinical practice. Methods: The survey was conducted online using the “google survey” by the BTM committee authorized by the Korean Society for Bone and Mineral Research. Results: Total 108 clinicians responded the survey. Most of the respondents prescribed BTMs (80.6%) when they prescribed anti-osteoporotic medications (AOMs). The most frequently prescribed bone resorption and formation markers were serum C-terminal telopeptide of type I collagen (90.7%) and osteocalcin (65.1%), respectively. BTMs were mostly prescribed before starting AOMs (90.8%) and used for the purpose of evaluating treatment response (74.4%). Treatment response and compliance to AOMs were evaluated according to the change of absolute value of BTMs (55.1%). The respondents complained difficulties in the interpretation of BTMs (33.3%), the choice of proper BTMs (17.2%), and the proper sample preparation and handling (13.8%). Conclusions: In Korea, most of clinicians recognized the benefit of BTMs in the management of osteoporosis. However, there are limitations in the broad use of these markers in clinical practice. Therefore, a clear recommendation for BTM in Korea enhances their use in clinical practice.
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참고문헌 (26)
참고문헌 신청
Burge R / 2007 / Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025 / J Bone Miner Res 22:465~475
Kang HY / 2010 / Incidence and mortality of hip fracture among the elderly population in South Korea: a population-based study using the national health insurance claims data / BMC Public Health 10:230
Kanis JA / 2008 / A reference standard for the description of osteoporosis / Bone 42:467~475
Kanis JA / 1994 / The diagnosis of osteoporosis / J Bone Miner Res 9:1137~1141
Garnero P / 1996 / Markers of bone resorption predict hip fracture in elderly women: the EPIDOS Prospective Study / J Bone Miner Res 11:1531~1538
Kang HY / 2010 / Incidence and mortality of hip fracture among the elderly population in South Korea: a population-based study using the national health insurance claims data / BMC Public Health 10:230
Kanis JA / 2008 / A reference standard for the description of osteoporosis / Bone 42:467~475
Kanis JA / 1994 / The diagnosis of osteoporosis / J Bone Miner Res 9:1137~1141
Garnero P / 1996 / Markers of bone resorption predict hip fracture in elderly women: the EPIDOS Prospective Study / J Bone Miner Res 11:1531~1538
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