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논문 기본 정보

자료유형
학술저널
저자정보
김성훈 (국립나주병원) 김경민 (국립나주병원) 윤보현 (국립나주병원) 정하란 (국립나주병원) 정유란 (국립나주병원) 윤현주 (국립나주병원) 차용호 (국립나주병원) 송제헌 (국립나주병원) 시영화 (국립나주병원)
저널정보
대한생물치료정신의학회 생물치료정신의학 생물치료정신의학 제27권 제1호(통권 제60호)
발행연도
2021.2
수록면
12 - 24 (13page)

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Objectives:This study was aimed to investigate the changes in metabolic syndrome (MetS) status and long-term impact of its components over a 10-year period in severe mental illness (SMI) patients in a national mental hospital.
Methods:A total of 93 patients (schizophrenia=88, bipolar disorder=5) who met the diagnosis of Diagnostic and Statistical Manual of Mental Disorders, fourth edition, text revision (DSM-IV-TR) and participated in the MetS study in 2011 were included. MetS was defined by revised National Cholesterol Education Program-Adult Treatment Panel III (revised NCEP-ATP-III) guidelines.
Results:The prevalence of MetS was significantly increased from 40.9% in 2011 to 60.2% in 2020. There were significant differences in admission status and hospitalization months, compared to the groups with and without MetS. Upon reviewing the changes over a decade, systolic blood pressure (SBP) was a significant factor in the group without MetS. In the group with MetS, SBP, waist circumference, and BMI (body mass index) were significant factors. Multiple logistic regression analysis revealed that hospitalization during follow-up periods [odds ratio (OR)=0.969, 95% confidence interval (CI): 0.948-0.991] and BMI (OR=1.426, 95% CI: 1.196-1.701) were significantly associated with MetS in subjects.
Conclusion:The prevalence of MetS in patients with SMI significantly increased over time. The admission status and hospitalization were also confirmed to be the significant values of MetS.

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UCI(KEPA) : I410-ECN-0101-2021-512-001586237