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- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.2
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The emergence of a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has become a significant health concern worldwide. Undoubtedly, a better understanding of the innate and adaptive immune responses against SARS-CoV-2 and its relationship with the coronavirus disease 2019 (COVID-19) pathogenesis will be the sole basis for developing and applying therapeutics. This review will summarize the published results that relate to innate immune responses against infections with human coronaviruses including SARS-CoV-1 and SARS-CoV-2 in both humans and animal models. The topics encompass the innate immune sensing of the virus to the dysregulation of various innate immune cells during infection and disease progression.
목차
ABSTRACT
INTRODUCTION
INNATE SENSING OF SARS-CoV-2
INNATE IMMUNE CELLS IN HUMANS
INNATE IMMUNE RESPONSES IN ANIMAL MODELS FOR SARS-CoV-2 INFECTION
CONCLUSION
REFERENCES
참고문헌 (95)
참고문헌 신청
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Shun-Chin Yang / 2021 / Understanding the role of neutrophils in acute respiratory distress syndrome / Biomedical Journal 44(4):439~446
Akira S / 2006 / Pathogen recognition and innate immunity / Cell 124:783~801
Scheuplein VA / 2015 / High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus / J Virol 89:3859~3869
Al-Qahtani AA / 2017 / Middle east respiratory syndrome corona virus spike glycoprotein suppresses macrophage responses via DPP4-mediated induction of IRAK-M and PPARγ / Oncotarget 8:9053~9066
Shun-Chin Yang / 2021 / Understanding the role of neutrophils in acute respiratory distress syndrome / Biomedical Journal 44(4):439~446
Akira S / 2006 / Pathogen recognition and innate immunity / Cell 124:783~801
Scheuplein VA / 2015 / High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus / J Virol 89:3859~3869
Al-Qahtani AA / 2017 / Middle east respiratory syndrome corona virus spike glycoprotein suppresses macrophage responses via DPP4-mediated induction of IRAK-M and PPARγ / Oncotarget 8:9053~9066
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