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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.7
- 수록면
- 221 - 221 (1page)
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Hepatocyte cell systems for in vitro assessment include hepatoma cell lines and normal hepatocyte cultures used in toxicity and metabolism of drugs. However, each cell line has its own characteristics. Induced pluripotent stem cells(iPSC), which can be differentiated to hepatocytes and providing a limitless supply of cells with hepatocyte characteristics that can mimic the physiology of liver, has been one of the best ways to portray the in vivo system. Thus, the objective of the present study was to compare between HepG2 cell line and iPSC-derived hepatocytes to conclude which is the good model for preclinical in vitro drug screening studies. We evaluated cytoto ... 전체 초록 보기
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