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논문 기본 정보

자료유형
학술저널
저자정보
김인혜 (신라대학교) 이재화 (신라대학교)
저널정보
한국생물공학회 KSBB Journal KSBB Journal Vol.36 No.3(Wn.178)
발행연도
2021.9
수록면
209 - 215 (7page)
DOI
10.7841/ksbbj.2021.36.3.209

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초록· 키워드

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Pleurotus nebrodensis have been used as a traditional remedy and a food source. Our study focuses on figuring out the possibility of Pleurotus nebrodensis as cosmetic materials. We examined anti-oxidant, anti-wrinkle, anti-inflammation and whitening effects. The SOD-like activity was 69.7 ± 2.31 at 125 ㎍/mL, compared to the standard sample L-ascorbic acid 1 mM 34.7 ± 0.79. It was 11.5 ± 0.27 ㎎/g Naringin base and 64 ± 1.45 GAE (Gallic acid) base as a measurement result of total flavonoid and total polyphenol contents. GME showed 24.5% (L-tyrosine), 16.6% (L-DOPA) of tyrosinase inhibition assay, respectively. In elastase inhibition assay showed 36.2% of inhibition at a concentrations 200 ㎍/mL, tyrosinase and elastase activation were found to inhibited dose-dependent. As a result of measuring the collagen precursor pro-collagen type 1, the amount of collagen synthesis was 434 ng/mL at a concentration of 500 ㎍/mL. The higher the concentration of GME the greater the wrinkle reduction and whitening effects. Anti-inflammatory activites measured nitric oxide (NO) and cell viability in LPS-induced macrophage RAW264.7 cell, it was found to inhibit NO production in a concentration-dependent manner. These results suggest methanol extracted Pleurotus nebrodensis has excellent activities in the anti-wrinkle, anti-inflammation and whitening. Therefore, Giant mushroom Pleurotus nebrodensis may have value as the potential cosmetic formulations.

목차

Abstract
1. INTRODUCTION
2. MATERIALS AND METHODS
3. RESULTS AND DISCUSSION
4. CONCLUSION
REFERENCES

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UCI(KEPA) : I410-ECN-0101-2021-470-002144850