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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 109 - 117 (9page)
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Lymph node metastasis is regarded as an indubitable prognostic factor for predicting disease recurrence and survival in patients with colorectal cancer. Lymph node status based on examination of a resected specimen is a key element of the current staging system and is also a crucial factor to determine use of adjuvant chemotherapy after surgical resection. However, the current tumor-node-metastasis (TNM) staging system only incorporates the number of metastatic lymph nodes in the N category. Numerous attempts have been made to supplement this simplified N staging including lymph node ratio, distribution of metastatic lymph nodes, tumor deposits, or extracapsular invasion. In addition, several attempts have been made to identify more specific prognostic factors in resected colorectal specimens than lymph node status. In this review, we will discuss controversies in lymph node staging and factors that may influence survival beyond lymph node status.
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참고문헌 (91)
참고문헌 신청
Nelson H / 2001 / Guidelines 2000 for colon and rectal cancer surgery / J Natl Cancer Inst 93:583~596
Greene FL / 2002 / A new TNM staging strategy for node-positive(stage III)colon cancer : an analysis of 50, 042 patients / Ann Surg 236:416~421
Gunderson LL / 2010 / Revised TN categorization for colon cancer based on national survival outcomes data / J Clin Oncol 28:264~271
Pereira ER / 2015 / The lymph node microenvironment and its role in the progression of metastatic cancer / Semin Cell Dev Biol 38:98~105
Ceelen W / 2010 / Prognostic value of the lymph node ratio in stage III colorectal cancer : a systematic review / Ann Surg Oncol 17:2847~2855
Greene FL / 2002 / A new TNM staging strategy for node-positive(stage III)colon cancer : an analysis of 50, 042 patients / Ann Surg 236:416~421
Gunderson LL / 2010 / Revised TN categorization for colon cancer based on national survival outcomes data / J Clin Oncol 28:264~271
Pereira ER / 2015 / The lymph node microenvironment and its role in the progression of metastatic cancer / Semin Cell Dev Biol 38:98~105
Ceelen W / 2010 / Prognostic value of the lymph node ratio in stage III colorectal cancer : a systematic review / Ann Surg Oncol 17:2847~2855
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