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자료유형
학술저널
저자정보
민지영 (연세대학교 의과대학 마취통증의학교실) 이정림 (연세대학교 의과대학 마취통증의학교실) 김현일 (연세대학교 의과대학 마취통증의학교실) 변효진 (연세대학교 의과대학 마취통증의학교실)
저널정보
대한응급의학회 Clinical and Experimental Emergency Medicine Clinical and Experimental Emergency Medicine Vol.6 No.2
발행연도
2019.1
수록면
119 - 124 (6page)

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Objective Children are sedated before undergoing diagnostic imaging tests in emergency medi­cine or pediatric sedation anesthesia units. The aim of this study was to identify variables poten­tially affecting the dose of ketamine required for induction of sedation in pediatric patients un­dergoing diagnostic imaging.Methods This retrospective study included children aged 0 to 18 years who underwent sedation with ketamine for computed tomography or magnetic resonance imaging in the pediatric seda­tion anesthesia unit of a tertiary medical center between January 2011 and August 2016. The children’s hemodynamic status and depth of sedation were monitored during the examination. We recorded data on demographics, categories of imaging tests, ketamine doses administered, adverse events, respiratory interventions, and duration of sedation. Data for patients who expe­rienced adverse events were excluded.Results Sixty-six patients were included in the final analysis. Univariate linear regression analysis revealed that patient age, height, and body surface area (BSA) affected the sedative dose of ket­amine administered. These three variables showed multicollinearity in multivariate linear regres­sion analysis and were analyzed in three separate models. The model with the highest adjusted R-squared value suggested the following equation for determination of the dose of ketamine re­quired to induce sedation: ketamine dose (mg)=-1.62+0.7×age (months)+36.36×BSA (m2).Conclusion Variables such as age and BSA should be considered when estimating the dose of ketamine required for induction of sedation in pediatric patients.

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