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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Over the past few decades, the survival rates of childhood acute leukemia have improved remarkably through treatment in risk-stratified prospective multicenter studies, and treatment protocols have evolved according to prognostic factors and treatment response. Recently, new molecular prognostic factors have been discovered through leukemic genome studies, and new subtypes with independent gene expression profiles have also been found. Furthermore, candidate mutations for target agents are being discovered, which will broaden therapeutic options for patients with poor prognostic factors. New drugs are currently being evaluated in clinical trials, and immunotherapy is now attracting interest in the treatment of recurrent or refractory disease in pediatric acute leukemia.
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참고문헌 (25)
참고문헌 신청
Pui CH / 2004 / Childhood and adolescent lymphoid and myeloid leukemia / Hematology Am Soc Hematol Educ Program :118~145
Pui CH / 2008 / Acute lymphoblastic leukaemia / Lancet 371:1030~1043
Hunger SP / 2012 / Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: a report from the childrenʼs oncology group / J Clin Oncol 30:1663~1669
김지은 / 2016 / Frequency and Clinical Characteristics of Intrachromosomal Amplification of Chromosome 21 in Korean Childhood B-lineage Acute Lymphoblastic Leukemia / Annals of Laboratory Medicine 36(5):475~480
Pui CH / 2002 / Outcome of treatment in childhood acute lymphoblastic leukaemia with rearrangements of the 11q23 chromosomal region / Lancet 359:1909~1915
Pui CH / 2008 / Acute lymphoblastic leukaemia / Lancet 371:1030~1043
Hunger SP / 2012 / Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: a report from the childrenʼs oncology group / J Clin Oncol 30:1663~1669
김지은 / 2016 / Frequency and Clinical Characteristics of Intrachromosomal Amplification of Chromosome 21 in Korean Childhood B-lineage Acute Lymphoblastic Leukemia / Annals of Laboratory Medicine 36(5):475~480
Pui CH / 2002 / Outcome of treatment in childhood acute lymphoblastic leukaemia with rearrangements of the 11q23 chromosomal region / Lancet 359:1909~1915
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