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논문 기본 정보

자료유형
학술저널
저자정보
Kwang-Chae Joo (Department of Family Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, S) Da-Hye Son (Department of Family Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, S) Jae-Min Park (Department of Family Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, S)
저널정보
대한가정의학회 Korean Journal of Family Medicine Korean Journal of Family Medicine 제43권 제3호
발행연도
2022.5
수록면
199 - 205 (7page)
DOI
10.4082/kjfm.21.0138

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Background: Evidence regarding the association between handgrip strength (HGS) and insulin resistance in a non-diabetic population is scarce. This study aimed to investigate the association between relative HGS and insulin resistance in older men without diabetes, using a representative sample of the Korean male population.Methods: The study population comprised 206 participants aged 65?80 years, selected from the 2015 Korea Na-tional Health and Nutrition Examination Survey. Insulin resistance was defined as the upper tertile of the homeo-static model assessment of insulin resistance (HOMA-IR). Odds ratios and 95% confidence intervals for insulin re-sistance were assessed using multiple logistic regression analyses after adjusting for confounding variables.Results: The prevalence of insulin resistance decreased with increasing relative HGS. The prevalence in the T1, T2, and T3 groups was 46.0%, 32.2%, and 26.4%, respectively. Compared with the individuals in the highest tertile of relative HGS, the odds ratio (95% confidence interval) for insulin resistance in individuals in the lowest quartile was 2.82 (1.10?7.21) after adjusting for age, smoking, alcohol consumption, aerobic exercise, resistance exercise, systolic blood pressure, total cholesterol, residential area, household income, and education level.Conclusion: Lower relative HGS was inversely associated with an increased risk of insulin resistance in older Kore-an men without diabetes. In clinical practice, relative HGS, which is a simple and inexpensive tool, could be a use-ful measure for identifying older men with insulin resistance. Moreover, these findings suggest that muscle strengthening exercises should be considered to reduce insulin resistance and increase insulin sensitivity.

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