메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Juliana de Brito Rangel (Federal University of Rio de Janeiro State (UNIRIO) Rio de Janeiro Brazil) Alessandra Grasso Giglio (Federal University of Rio de Janeiro State (UNIRIO) Rio de Janeiro Brazil) Cristiane Lemos Cardozo (Brazilian National Cancer Institute (INCA) Rio de Janeiro Brazil) Anke Bergmann (Brazilian National Cancer Institute (INCA) Rio de Janeiro Brazil) Luiz Claudio Santos Thuler (Instituto Nacional do Câncer (INCA) Hospital do Câncer II Santo Cristo Rio de Janeiro Brazil)
저널정보
대한부인종양학회 Journal of Gynecologic Oncology Journal of Gynecologic Oncology Vol.33 No.5
발행연도
2022.9
수록면
1 - 11 (11page)
DOI
https://doi.org/10.3802/jgo.2022.33.e58

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Objective: Cerebral metastasis (CM) in cervical cancer (CC) cases, although rare, results in high lethality rates. The present study aimed to assess CM incidence in a Brazilian reference CC center and evaluate the risk factors for CM development. Retrospective observational study of patients diagnosed with CC between 2010 and 2017. Methods: Cumulative CM incidence and incidence density were evaluated. Characteristics associated to CM development risks were identified using crude (cOR) or adjusted (aOR) odds ratios. Results: A total of 3,397 patients were included in this study. Patient age ranged from 18 to 101 years, with a mean age of 48.8±14.0. After a mean follow-up time of 3.2±2.1 years, 51 CM cases were identified, resulting in a cumulative incidence of 1.5% (95% confidence intervals [CI]=1.12?1.97) and an incidence density at the end of the 6th year of 27.4 per 1,000 women/ year. Advanced clinical stage (aOR=3.15; 95% CI=1.16?8.58; p=0.025), the presence of previous lung metastasis (aOR=4.04; 95% CI=1.82?8.94; p=0.001) and the adenocarcinoma (aOR=2.90; 95% CI=1.46?5.76; p=0.002), adenosquamous carcinoma (aOR=7.33; 95%CI=2.87?18.73; p<0.001), undifferentiated carcinoma (aOR=14.37; 95% CI=3.77?54.76;p<0.001) and neuroendocrine carcinoma (aOR=21.31; 95% CI=6.65?68.37, p<0.001) histological types were associated with a higher risk for CM development. CM risk was higher in the first years of follow-up, with no cases observed after the 6th year. Conclusion: CC patients in advanced clinical stages, displaying previous lung metastasis and non-squamous histological types are at high risk of developing CM.

목차

등록된 정보가 없습니다.

참고문헌 (0)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0