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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.12
- 수록면
- 954 - 958 (5page)
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Myxofibrosarcoma (MFS) is a histologic subtype of malignant fibrous histiocytoma (MFH),with a predominant myxoid component. MFS is characterized by locally aggressive behaviorand a high rate of local recurrence, however, with a good prognosis. Head and neck MFS accountsfor 3% of all cases of MFS. To date, only two cases of laryngeal MFS have been reported.
Owing to the rarity of MFS, the clinical characteristics and optimal treatment optionsremain controversial. Surgical resection with a clear margin is considered the treatment ofchoice. Compared to traditional MFS tumors, epithelioid variants have worse prognosis. Otherfactors associated with a poor prognosis of MFS tumors include inadequate surgical margins,large tumor size, old age, and high-grade tumors. Herein, we report a case of high-grade epithelioidvariant MFS located in the false vocal fold, requiring total laryngectomy to obtain anadequate surgical margin. To our knowledge, this is the first case report of epithelioid variantof high-grade MFS presenting in the larynx.
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참고문헌 (15)
참고문헌 신청
Farhood AI / 1990 / Soft tissue sarcomas of the head and neck in adults / Am J Surg 160(4):365~369
Potter BO / 2003 / Sarcomas of the head and neck / Surg Oncol Clin N Am 12(2):379~417
Fletcher C / 2013 / WHO classification of tumours of soft tissue and bone / IARC Press
Roland CL / 2016 / Myxofibrosarcoma / Surg Oncol Clin N Am 25(4):775~788
Weiss SW / 1977 / Myxoid variant of malignant fibrous histiocytoma / Cancer 39(4):1672~1685
Potter BO / 2003 / Sarcomas of the head and neck / Surg Oncol Clin N Am 12(2):379~417
Fletcher C / 2013 / WHO classification of tumours of soft tissue and bone / IARC Press
Roland CL / 2016 / Myxofibrosarcoma / Surg Oncol Clin N Am 25(4):775~788
Weiss SW / 1977 / Myxoid variant of malignant fibrous histiocytoma / Cancer 39(4):1672~1685
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