지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.12
- 수록면
- 943 - 960 (18page)
- DOI
- https://doi.org/10.4070/kcj.2021.0291
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초록· 키워드
오류제보하기
The limited ability of cardiomyocytes to proliferate is a major cause of mortality and morbidity in cardiovascular diseases. There exist therapies for cardiac regeneration that are cell-based as well as that involve bioactive molecules. However, delivery remains one of the major challenges impeding such therapies from having clinical impact. Recent advancements in biomaterials-based approaches for cardiac regeneration have shown promise in clinical trials and animal studies in improving cardiac function, promoting angiogenesis, and reducing adverse immune response. This review will focus on current clinical studies of three contemporary biomaterials-based approaches for cardiac regeneration (extracellular vesicles, injectable hydrogels, and cardiac patches), remaining challenges and shortcomings to be overcome, and future directions for the use of biomaterials to promote cardiac regeneration.
목차
등록된 정보가 없습니다.
참고문헌 (100)
참고문헌 신청
Virani SS / 2021 / Heart disease and stroke statistics-2021 update : a report from the American Heart Association / Circulation 143:e254~743
He L / 2017 / Cardiomyocyte proliferation : remove brakes and push accelerators / Cell Res 27:959~960
Ludhwani D / StatPearls. Heart transplantation rejection
Bar A / 2020 / Inducing endogenous cardiac regeneration: can biomaterials connect the dots? / Front Bioeng Biotechnol 8:126
Nussbaum J / 2007 / Transplantation of undifferentiated murine embryonic stem cells in the heart : teratoma formation and immune response / FASEB J 21:1345~1357
He L / 2017 / Cardiomyocyte proliferation : remove brakes and push accelerators / Cell Res 27:959~960
Ludhwani D / StatPearls. Heart transplantation rejection
Bar A / 2020 / Inducing endogenous cardiac regeneration: can biomaterials connect the dots? / Front Bioeng Biotechnol 8:126
Nussbaum J / 2007 / Transplantation of undifferentiated murine embryonic stem cells in the heart : teratoma formation and immune response / FASEB J 21:1345~1357
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