지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Psoriasis has been associated with various cardiovascular and metabolic comorbidities. Recently, there are studies reporting the association of psoriasis with renal diseases. However, there is little information on the safety and efficacy of biologic therapies used in psoriasis patients with renal failure. A 35-year-old man presented with psoriasis and chronic kidney disease (CKD) undergoing hemodialysis. Narrowband ultraviolet B (NBUVB) therapy was unsatisfactory. After treatment with guselkumab, psoriasis area and severity index (PASI) score decreased from 11 to 1.2 after 12 weeks. A 52- year old-man and a 39-year-old woman presented with psoriasis and CKD. Treatment with NBUVB and methotrexate did not meet the treatment goal. After treatment with ixekizumab, PASI score decreased from 11 to 2 and 12 to 1.4 after 12 weeks, respectively. All of them have maintained good clinical responses without side effects. Herein, we report successful cases of using guselkumab and ixekizumab to treat psoriasis patients with renal failure suggesting guselkumab and ixekizumab as safe treatment options.
목차
등록된 정보가 없습니다.
참고문헌 (13)
참고문헌 신청
Mikhaylov D / 2019 / Systemic psoriasis therapies and comorbid disease in patients with psoriasis: a review of potential risks and benefits / J Clin Aesthet Dermatol 12:46~54
Rustin MH / 2012 / Long-term safety of biologics in the treatment of moderate-to-severe plaque psoriasis: review of current data / Br J Dermatol 167(Suppl 3):3~11
Wan J / 2013 / Risk of moderate to advanced kidney disease in patients with psoriasis:population based cohort study / BMJ 347:f5961
Chi CC / 2015 / Risk of incident chronic kidney disease and end-stage renal disease in patients with psoriasis: a nationwide population-based cohort study / J Dermatol Sci 7:232~238
Visconti L / 2016 / Kidney disease and psoriasis: novel evidences beyond old concepts / Clin Rheumatol 35:297~302
Rustin MH / 2012 / Long-term safety of biologics in the treatment of moderate-to-severe plaque psoriasis: review of current data / Br J Dermatol 167(Suppl 3):3~11
Wan J / 2013 / Risk of moderate to advanced kidney disease in patients with psoriasis:population based cohort study / BMJ 347:f5961
Chi CC / 2015 / Risk of incident chronic kidney disease and end-stage renal disease in patients with psoriasis: a nationwide population-based cohort study / J Dermatol Sci 7:232~238
Visconti L / 2016 / Kidney disease and psoriasis: novel evidences beyond old concepts / Clin Rheumatol 35:297~302
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