지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.3
- 수록면
- 1 - 6 (6page)
- DOI
- http://dx.doi.org/10.5230/jgc.2014.14.1.1
이용수
초록· 키워드
오류제보하기
Aerobic glycolysis has been the most important hypothesis in cancer metabolism. It seems to be related to increased bioenergetic and biosynthetic needs in rapidly proliferating cancer cells. To this end, F-18 fluorodeoxyglucose (FDG), a glucose analog, became widely popular for the detection of malignancies combined with positron emission tomography/computed tomography (PET/CT). Although the potential roles of FDG PET/CT in primary tumor detection are not fully established, it seems to have a limited sensitivity in detecting early gastric cancer and mainly signet ring or non-solid types of advanced gastric cancer. In evaluating lymph node metastases, the location of lymph nodes and the degree of FDG uptake in primary tumors appear to be important factors affecting the diagnostic accuracy of PET/CT. In spite of the limited sensitivity, the high specificity of PET/CT for lymph node metastases may play an important role in changing the extent of lymphadenectomy or reducing futile laparotomies. For peritoneal metastases, PET/CT seems to have a poorer sensitivity buta better specificity than CT. The roles of PET/CT in the evaluation of other distant metastases are yet to be known. Studies including primary tumors with low FDG uptake or peritoneal recurrence seem suffer from poorer diagnostic performance for the detection of recurrent gastric cancer. There are only a few reports using FDG PET/CT to predict response to neoadjuvant or adjuvant chemotherapy. A complete metabolic response seems to be predictive of more favorable prognosis.
목차
등록된 정보가 없습니다.
참고문헌 (33)
참고문헌 신청
Warburg O / 1927 / The metabolism of tumors in the body / J Gen Physiol 8:519~530
Hanahan D / 2011 / Hallmarks of cancer: the next generation / Cell 144:646~674
Stahl A / 2003 / FDG PET imaging of locally advanced gastric carcinomas: correlation with endoscopic and histopathological findings / Eur J Nucl Med Mol Imaging 30:288~295
Mochiki E / 2004 / Evaluation of 18F-2-deoxy-2-fluoro-D-glucose positron emission tomography for gastric cancer / World J Surg 28:247~253
Yun M / 2005 / Lymph node staging of gastric cancer using (18)F-FDG PET: a comparison study with CT / J Nucl Med 46:1582~1588
Hanahan D / 2011 / Hallmarks of cancer: the next generation / Cell 144:646~674
Stahl A / 2003 / FDG PET imaging of locally advanced gastric carcinomas: correlation with endoscopic and histopathological findings / Eur J Nucl Med Mol Imaging 30:288~295
Mochiki E / 2004 / Evaluation of 18F-2-deoxy-2-fluoro-D-glucose positron emission tomography for gastric cancer / World J Surg 28:247~253
Yun M / 2005 / Lymph node staging of gastric cancer using (18)F-FDG PET: a comparison study with CT / J Nucl Med 46:1582~1588
이 논문의 저자 정보
최근 본 자료
댓글(0)
0