지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 1 - 4 (4page)
- DOI
- https://doi.org/10.15279/kpba.2015.20.1.1
이용수
초록· 키워드
오류제보하기
Pancreatic cancer is still one of the most dreadful malignancies with 5-year survival of 5%. The lack of effective diagnostic tools for early detection of pancreatic cancer is the major factor for the poor prognosis of pancreatic cancer. Considering the relatively lower incidence of pancreatic cancer, it seems to be reasonable to find and investigate the high risk group of pancreatic cancer rather than to screen general population. During the last 2 decades, several epidemiologic and genetic high risk groups of pancreatic cancer were found. Especially, western countries including US have been taking care of genetic high risk group and reported several meaningful outcomes. With advances of understanding molecular carcinogenesis and progression of pancreatic cancer, the effort to find specific biomarkers for both detection and treatment of pancreatic cancer has been overwhelmed. Various types of biomarkers including protein, microRNA, exosomes or circulating tumor cells itself have been under investigations. Although there has been no single biomarker which can overcome CA19-9 in serum to date. It will be worthwhile to wait for more potent biomarker which can be used for early diagnosis and treatment of pancreatic cancer in near future.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Siegel R / 2012 / Cancer statistics, 2012 / CA Cancer J Clin 62:10~29
Hruban RH / 2001 / Pancreatic intraepithelial neoplasia : a new nomenclature and classification system for pancreatic duct lesions / Am J Surg Pathol 25:579~586
Ottenhof NA / 2009 / Pancreatic intraepithelial neoplasia and pancreatic tumorigenesis : of mice and men / Arch Pathol Lab Med 133:375~381
Sipos B / 2009 / Pancreatic intraepithelial neoplasia revisited and updated / Pancreatology 9:45~54
Hingorani SR / 2003 / Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse / Cancer Cell 4:437~450
Hruban RH / 2001 / Pancreatic intraepithelial neoplasia : a new nomenclature and classification system for pancreatic duct lesions / Am J Surg Pathol 25:579~586
Ottenhof NA / 2009 / Pancreatic intraepithelial neoplasia and pancreatic tumorigenesis : of mice and men / Arch Pathol Lab Med 133:375~381
Sipos B / 2009 / Pancreatic intraepithelial neoplasia revisited and updated / Pancreatology 9:45~54
Hingorani SR / 2003 / Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse / Cancer Cell 4:437~450
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