Colorectal surgical management of colitis induced by vasculitis in the absence of inflammatory bowel disease: a case report and literature review

Jessica A. Paynter; Kirby R.Qin; Georgia Seamer; Ruchira Fernando; Janelle Brennan; Chun Hin Angus Lee

doi:10.3393/ac.2022.00584.0083

추천

검색

자료유형: 학술저널

저자정보: Jessica A. Paynter (Department of General Surgery Bendigo Health) Kirby R.Qin (Department of Urology Austin Health) Georgia Seamer (Monash University School of Rural Health Bendigo) Ruchira Fernando (Australian Clinical Laboratory Pathology) Janelle Brennan (Department of Urology Bendigo Health) Chun Hin Angus Lee (Department of General Surgery Bendigo Health)

저널정보: 대한대장항문학회 Annals of Coloproctology Annals of Coloproctolgy Vol.39 No.3

발행연도: 2023.6

수록면: 193 - 203 (11page)

DOI: 10.3393/ac.2022.00584.0083

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Colitis caused by vasculitis is a rare and poorly understood pathology. Little evidence exists on its clinical presentation, path to diagnosis, and surgical management. In this report, we present a case report and literature review. A healthy 20-year-old male patient presented with hemorrhagic colitis requiring total colectomy with end ileostomy. Pathological examination showed pancolitis with multiple ulcers, transmural inflammation, hemorrhage, and microvascular thrombosis. Extensive serological testing revealed elevated cytoplasmic antineutrophil cytoplasmic antibody (c-ANCA) and eosinophilia, leading to a diagnosis of eosinophilic granulomatosis with polyangiitis (EGPA) and vasculitis-induced colitis. A literature review was subsequently conducted. Nineteen studies were found documenting vasculitis-induced colitis in the absence of inflammatory bowel disease (IBD). Systemic signs of vasculitis, hemorrhagic colitis, and progression to fulminant colitis were present. Of all patients, 40.0% required colorectal surgery and 62.5% of those patients received a stoma; 25% underwent emergency surgery following failed immunosuppression. All cases relied on clinical correlation with serology and/or histopathology to reach a final diagnosis. We report a case of vasculitis-induced colitis caused by c-ANCA−positive EGPA. The review shows that vasculitis-induced colitis without IBD is an important differential that clinicians should be aware of in patients presenting with colitis.

#Colitis #Vasculitis #Colorectal surgery #General surgery

참고문헌 (0)

참고문헌 신청

참고문헌이 DBpia에서 서비스 중이라면, [참고문헌 신청]을 통해 등록해보세요

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!