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논문 기본 정보

자료유형
학술저널
저자정보
정유훈 (Department of Neurology Dongsan Medical Center Keimyung University School of Medicine Daegu Korea) 최종석 (Department of Neurology Korea University College of Medicine Seoul Korea) Byung-Jo Kim (Department of Neurology Korea University College of Medicine Seoul Korea) Hung Youl Seok (Department of Neurology Dongsan Medical Center Keimyung University School of Medicine Daegu Korea)
저널정보
영남대학교 의과대학 Journal of Yeungnam Medical Science Journal of Yeungnam Medical Science 제40권 제2호
발행연도
2023.4
수록면
198 - 201 (4page)
DOI
10.12701/jyms.2021.01494

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Invasive sphenoid sinus aspergillosis can mimic Tolosa-Hunt syndrome (THS), leading to frequent misdiagnoses and potentially fatal consequences. We report a case of invasive sphenoid sinus aspergillosis initially misdiagnosed as THS. A 79-year-old man presented with right periorbital pain, ophthalmoplegia, and loss of vision. Initial evaluations including magnetic resonance imaging (MRI), were normal. He was first diagnosed with THS based on clinical features. The disease progressed despite high-dose intravenous steroid treatment, and an enhancing mass-like lesion was found in the right orbital apex, cavernous sinus, and sphenoid sinus on follow-up MRI. Aspergillosis was eventually confirmed by sphenoid sinus biopsy. The patient developed cerebral infarction and finally died despite being treated with amphotericin B. Given that invasive sphenoid sinus aspergillosis may initially resemble THS, high suspicion and rapid histological examination are important for diagnosis.

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