지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.1
- 수록면
- 1 - 10 (10page)
- DOI
- https://doi.org/10.3802/jgo.2023.34.e8
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초록· 키워드
오류제보하기
Objective: To compare the safety between cer vical conization (CC) alone and hysterectomyfor patients with adenocarcinoma in situ (AIS) of the cer vix.
Methods: Patients diagnosed with AIS after CC during 2007–2021 were identified bycomputerized databases at Women’s Hospital of Zhejiang University School of Medicine.
A total of 453 AIS patients were divided into 2 groups according to uterus preser vation:hysterectomy group (n=300) and CC(s) alone group (n=153). The prevalence of residualdisease and disease recurrence was compared between patients treated by CC(s) alone andhysterectomy. The prevalence of residual disease in specimens from women who had ahysterectomy and repeat CC were compared between positive and negative margins of CC.
The factors influencing residual disease and disease recurrence were assessed.
Results: Among 310 specimens from women who had a hysterectomy or repeat CC, theprevalence of residual disease was 50.6% (45/89) for a positive margin and 2.3% (5/221) for anegative margin (p=0.000). Four patients had recurrence of vaginal intraepithelial neoplasiain those treated by hysterectomy and one had recurrence of cer vical squamous intraepithelialneoplasia in those treated by CC(s) alone. The prevalence of recurrence was 0.7% (1/153) forCC(s) alone and 1.3% (4/300) for hysterectomy (p=0.431). Hysterectomy did not influenceresidual disease or disease recurrence.
Conclusion: CC is an efficacious and safe option for patients with AIS of the cer vix providedthe margin is negative.
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