지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.12
- 수록면
- 209 - 218 (10page)
- DOI
- 10.22889/KJP.2023.54.4.209
이용수
초록· 키워드
오류제보하기
Skin aging is caused by structural changes in the extracellular matrix (ECM) due to internal and external factors. It is characterized by decreased skin moisture, increased skin roughness, increased skin wrinkles, and decreased skin elasticity. In this study, Elastase and Collagenase inhibitory activities and SOD, CAT, and GSH-Px activities were confirmed in HaCaT cells, and Collagen-I content and skin elasticity were also confirmed in response to UVB irradiation in HR-1 hairless mice. In addition, a double-blind, randomized, placebo-controlled study was conducted on the effects of oral administration of NP-2007 in 84 women. In the group that consumed NP-2007 or placebo, the amount of skin moisture, trans-epidermal water loss (TEWL), mass of skin keratin, skin asperity (Ra, Rz), eye wrinkle, and skin elasticity were checked. Compared to the placebo group, significant changes were confirmed at all-time points after 6 and 12 weeks of intake. This study was investigated the potential of oral administration of NP-2007 as a functional food material that improves skin.
목차
Abstract
재료 및 방법
결과 및 고찰
결론
인용문헌
참고문헌 (22)
참고문헌 신청
Holbrook, K. (1991) Structure and function of the developing human skin. In Goldsmith. L. (ed.), Physiology, biochemistry, and molecular biology of the skin, 63-110, Oxford University Press, Oxford.
Choi, Y. S., You, C. E., Park, M. Y., Son, S. J. and Whang, K. U. (2006) A study on clinical features and laboratory findings according to the severity of atopic dermatitis. Korean J. Dermatol. 44: 824-829.
Kim, H., Park, K. H., Yeo, J. H., Lee, K. G., Jeong, D. H., Kim, S. H. and Cho, Y. (2006) Dietary effect of silk protein sericin or fibroin on plasma and epidermal amino acid concentration of NC/Nga mice. J. Nutr. Health 39: 520-528.
Stern, R. and Maibach, H. (2008) Hyaluronan in skin: aspects of aging and its pharmacologic modulation. Clin. Dermatol. 26: 106-122.
Coderch, L., López, O., Maza, A. and Parra, J. L. (2003) Ceramides and skin function. Am. J. Clin. Dermatol. 4: 107-129.
Choi, Y. S., You, C. E., Park, M. Y., Son, S. J. and Whang, K. U. (2006) A study on clinical features and laboratory findings according to the severity of atopic dermatitis. Korean J. Dermatol. 44: 824-829.
Kim, H., Park, K. H., Yeo, J. H., Lee, K. G., Jeong, D. H., Kim, S. H. and Cho, Y. (2006) Dietary effect of silk protein sericin or fibroin on plasma and epidermal amino acid concentration of NC/Nga mice. J. Nutr. Health 39: 520-528.
Stern, R. and Maibach, H. (2008) Hyaluronan in skin: aspects of aging and its pharmacologic modulation. Clin. Dermatol. 26: 106-122.
Coderch, L., López, O., Maza, A. and Parra, J. L. (2003) Ceramides and skin function. Am. J. Clin. Dermatol. 4: 107-129.
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