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논문 기본 정보

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학술저널
저자정보
Park Jae-Min (Department of Family Medicine, Uijeongbu Eulji Medical Center, Eulji University, Uijeongbu, Korea.Department of Medicine, Graduate School of Medicine, Yonsei University, Seoul, Korea.) Koo Hye Yeon (Department of Family Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.Department of Family Medicine, Seoul National University College of Medicine, Seoul, Korea.) Lee Jae-ryun (Department of Family Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.) Lee Hyejin (Department of Family Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.Department of Family Medicine, Seoul National University College of Medicine, Seoul, Korea.) Lee Jin Yong (Department of Health Policy and Management, Seoul National University College of Medicine, Seoul, Korea.Public Healthcare Center, Seoul National University Hospital, Seoul, Korea.Institute o)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.39 No.2
발행연도
2024.1
수록면
1 - 10 (10page)
DOI
10.3346/jkms.2024.39.e6

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초록· 키워드

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Background: We aimed to investigate mortality, severity, and risk of hospitalization in coronavirus disease 2019 (COVID-19) patients with cancer. Methods: Data of all patients aged 40–79 years from the Korean Disease Control and Prevention Agency-COVID19-National Health Insurance Service who were diagnosed with COVID-19 between January 1, 2020 and March 31, 2022, in Korea were included. After 1:1 propensity score matching, 397,050 patients with cancer and 397,050 patients without cancer were enrolled in the main analysis. A cancer survivor was defined as a patient who had survived 5 or more years since the diagnosis of cancer. Multiple logistic regression analysis was performed to compare the risk of COVID-19 according to the diagnosis of cancer and time since diagnosis. Results: Cancer, old age, male sex, incomplete vaccination against COVID-19, lower economic status, and a higher Charlson comorbidity index were associated with an increased risk of hospitalization, hospitalization with severe state, and death. Compared to patients without cancer, the adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for hospitalization, hospitalization with severe state, and death in patients with cancer were 1.09 (1.08–1.11), 1.17 (1.11–1.24), and 1.94 (1.84–2.05), respectively. Compared to patients without cancer, the ORs (95% CIs) for hospitalization in cancer survivors, patients with cancer diagnosed 2–5 years, 1–2 years, and < 1 year ago were 0.96 (0.94–0.98), 1.10 (1.07–1.13), 1.30 (1.25–1.34), and 1.82 (1.77–1.87), respectively; the ORs (95% CIs) for hospitalization for severe disease among these patients were 0.90 (0.85–0.97), 1.22 (1.12–1.32), 1.60 (1.43–1.79), and 2.29 (2.09–2.50), respectively. Conclusion: The risks of death, severe state, and hospitalization due to COVID-19 were higher in patients with cancer than in those without; the more recent the diagnosis, the higher the aforementioned risks. Cancer survivors had a lower risk of hospitalization and hospitalization with severe disease than those without cancer.
#COVID-19 #Cancer #Cancer Survivors #Mortality #Severity

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