지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.6
- 수록면
- 1 - 15 (15page)
- DOI
- 10.1038/s12276-024-01239-6
이용수
초록· 키워드
오류제보하기
It is apparent that various functional units within the cellular machinery are derived from RNAs. The evolution of sequencing techniques has resulted in significant insights into approaches for transcriptome studies. Organisms utilize RNA to govern cellular systems, and a heterogeneous class of RNAs is involved in regulatory functions. In particular, regulatory RNAs are increasingly recognized to participate in intricately functioning machinery across almost all levels of biological systems. These systems include those mediating chromatin arrangement, transcription, suborganelle stabilization, and posttranscriptional modifications. Any class of RNA exhibiting regulatory activity can be termed a class of regulatory RNA and is typically represented by noncoding RNAs, which constitute a substantial portion of the genome. These RNAs function based on the principle of structural changes through cis and/or trans regulation to facilitate mutual RNA‒RNA, RNA‒DNA, and RNA‒protein interactions. It has not been clearly elucidated whether regulatory RNAs identified through deep sequencing actually function in the anticipated mechanisms. This review addresses the dominant properties of regulatory RNAs at various layers of the cellular machinery and covers regulatory activities, structural dynamics, modifications, associated molecules, and further challenges related to therapeutics and deep learning.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
RNA Therapy: Current Status and Future Potential
한국생물공학회 학술대회
2021 .10
-
Crosstalk between RNA silencing and RNA quality control in plants
BMB Reports
2023 .06
-
RNA therapy: rich history, various applications and unlimited future prospects
Experimental and Molecular Medicine
2022 .04
-
Pathogenic diversity of RNA variants and RNA variation-associated factors in cancer development
Experimental and Molecular Medicine
2020 .01
-
Understanding Confounding Effects of Blood Handling Strategies on RNA Quality and Transcriptomic Alteration Using RNA Sequencing
BioChip Journal
2021 .01
-
NMR Tools to Decipher Dynamic Structure of RNA
Journal of the Korean Magnetic Resonance Society
2017 .01
-
The roles and mechanisms of coding and noncoding RNA variations in cancer
Experimental and Molecular Medicine
2024 .09
-
Identifying the cellular location of brain cytoplasmic 200 RNA using an RNA-recognizing antibody
BMB Reports
2017 .06
-
Regulatory RNA: from molecular insights to therapeutic frontiers
Experimental and Molecular Medicine
2024 .06
-
Advances in Nanoparticles for Effective Delivery of RNA Therapeutics
BioChip Journal
2022 .06
-
Optimal design of synthetic circular RNAs
Experimental and Molecular Medicine
2024 .06
-
유전 알고리즘을 활용한 RNA 설계 방법론
한국정보과학회 학술발표논문집
2016 .06
-
Therapeutic Potential of Regulating Mitochondrial RNAs
한국생물공학회 학술대회
2022 .04
-
RNA Folding and the Non-equilibrium Action of RNA Chaperones
한국고분자학회 학술대회 연구논문 초록집
2024 .09
-
Deciphering the molecular mechanisms of epitranscriptome regulation in cancer
BMB Reports
2021 .01
-
Double Controlled Release of Therapeutic RNA Modules through Injectable DNA-RNA Hybrid Hydrogel
한국고분자학회 학술대회 연구논문 초록집
2021 .04
-
마이크로RNA와 유전자 연관성 예측 딥러닝 모델 개발 연구
한국통신학회 학술대회논문집
2021 .06
-
Artificial small RNAs for efficient gene silencing in Escherichia coli
한국생물공학회 학술대회
2016 .10
-
Molecular functions and therapeutic applications of exosomal noncoding RNAs in cancer
Experimental and Molecular Medicine
2022 .03
-
The roles of N6-methyladenosine and its target regulatory noncoding RNAs in tumors: classification, mechanisms, and potential therapeutic implications
Experimental and Molecular Medicine
2023 .03
최근 본 자료
댓글(0)
0