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논문 기본 정보

자료유형
학술저널
저자정보
Lee Yeji (Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea) Kim Taeil (Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea) Kim Dong Eon (Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea) Jo Eun Mi (Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea) Kim Da Woon (Department of Internal Medicine, Pusan National University School of Medicine, Yangsan, Republic of Korea) Kim Hyo Jin (Department of Internal Medicine, Pusan National University School of Medicine, Yangsan, Republic of Korea) 성은영 (부산대학교) 송상헌 (부산대학교) 이하린 (부산대학교)
저널정보
대한신장학회 Kidney Research and Clinical Practice Kidney Research and Clinical Practice Vol.43 No.4
발행연도
2024.7
수록면
518 - 527 (10page)
DOI
10.23876/j.krcp.23.312

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Background: Though acute kidney injury (AKI) is a prevalent complication in critically ill patients, knowledge on the epidemiological differences and clinical characteristics of patients with AKI admitted to medical and surgical intensive care units (ICUs) remains limited. Methods: Electronic medical records of patients in ICUs in Pusan National University Hospital and Pusan National University Hospital Yangsan, from January 2011 to December 2020, were retrospectively analyzed. Different characteristics of AKI between patients were analyzed. The contribution of AKI to the in-hospital mortality rate was assessed using a Cox proportional hazards model. Results: A total of 7,150 patients were included in this study. AKI was more frequent in medical (48.7%) than in surgical patients (19.7%), with the severity of AKI higher in medical patients. In surgical patients, hospital-acquired AKI was more frequent (51.0% vs. 49.0%), whereas community-acquired AKI was more common in medical patients (58.5% vs. 41.5%). 16.9% and 5.9% of medical and surgical patients died in the hospital, respectively. AKI affected patient groups to different degrees. In surgical patients, AKI patients had 4.778 folds higher risk of mortality (95% confidence interval [CI], 3.577–6.382; p < 0.001) than non-AKI patients; whereas in medical AKI patients, it was 1.239 (95% CI, 1.051–1.461; p = 0.01). Conclusion: While the prevalence of AKI itself is higher in medical patients, the impact of AKI on mortality was stronger in surgical patients compared to medical patients. This suggests that more attention is needed for perioperative patients to prevent and manage AKI.

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