지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 121 - 128 (8page)
이용수
초록· 키워드
오류제보하기
Background and Purpose Measuring the extent of the collateral blood vessels using computed tomography (CT) angiography source images may promote tissue survival and functional gain in acute ischemic stroke patients who are candidates for endovascular re¬canalization treatment.
Methods Of 5,558 acute stroke patients registered in a prospective clinical stroke registry, 104 met the selection criteria of endovascular recanalization treatment for internal cerebral artery or middle cerebral artery main-stem (M1) occlusions and presented for treatment ≤4 hours after the event. Using CT angiography source images, two independent and blinded reviewers measured the extent of collateral circulations at four regions, with good interrater reliability. The functional recovery at 3 months after stroke was used as an outcome variable.
Results Cases with a sufficient collateral circulation at the Sylvian fissure showed signifi¬cantly increased likelihood of having a modified Rankin Scale score of ≤2 at 3 months after stroke (adjusted odds ratio=3.03, 95% confidence interval=1.19–7.73, p=0.02), but the asso¬ciation became nonsignificant after adding the infarct volume to the model (p=0.65). The association between leptomeningeal convexity collaterals and functional recovery was no longer significant after adjusting for the infarct volume (p=0.28). The natural indirect effect of infarct volume on functional recovery was significant for both the Sylvian fissure (p=0.03) and leptomeningeal convexity (p=0.02) collaterals.
Conclusions The extent of collateral circulation at the Sylvian fissure was significantly as¬sociated with functional recovery, which may be mediated via the volume of the final infarc¬tion.
목차
등록된 정보가 없습니다.
참고문헌 (31)
참고문헌 신청
National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) / 2002 / Third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) final report / Circulation 106:3143~3421
VanderWeele TJ / 2015 / Explanation in Causal Inference : Methods for Mediation and Interaction / Oxford University Press
Kim BJ / 2015 / Trends in the effectiveness of endovascular recanalization for acute stroke: is a change taking place? / J Stroke Cerebrovasc Dis 24:866~873
McVerry F / 2012 / Systematic review of methods for assessing leptomeningeal collateral flow / AJNR Am J Neuroradiol 33:576~582
Calleja AI / 2013 / Collateral circulation on perfusion-computed tomography-source images predicts the response to stroke intravenous thrombolysis / Eur J Neurol 20:795~802
VanderWeele TJ / 2015 / Explanation in Causal Inference : Methods for Mediation and Interaction / Oxford University Press
Kim BJ / 2015 / Trends in the effectiveness of endovascular recanalization for acute stroke: is a change taking place? / J Stroke Cerebrovasc Dis 24:866~873
McVerry F / 2012 / Systematic review of methods for assessing leptomeningeal collateral flow / AJNR Am J Neuroradiol 33:576~582
Calleja AI / 2013 / Collateral circulation on perfusion-computed tomography-source images predicts the response to stroke intravenous thrombolysis / Eur J Neurol 20:795~802
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