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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 1,111 - 1,118 (8page)
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초록· 키워드
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Purpose: To investigate the association between long-term exposure to ambient air pollution and lung cancer incidence in Koreans.
Materials and Methods: This was a population-based case-control study covering 908 lung cancer patients and 908 controls selectedfrom a random sample of people within each Korean province and matched according to age, sex, and smoking status. We developed land-use regression models to estimate annual residential exposure to particulate matter (PM10) and nitrogen dioxide (NO2) over a 20-year exposure period. Logistic regression was used to estimate odds ratios (ORs) and their corresponding 95% confidence intervals (CI).
Results: Increases in lung cancer incidence (expressed as adjusted OR) were 1.09 (95% CI: 0.96−1.23) with a ten-unit increase in PM10 (μg/m3) and 1.10 (95% CI: 1.00−1.22) with a ten-unit increase in NO2 (ppb). Tendencies for stronger associations between air pollution and lung cancer incidence were noted among never smokers, among those with low fruit consumption, and among those with a higher education level. Air pollution was more strongly associated with squamous cell and small cell carcinomas than with adenocarcinoma of the lung.
Conclusion: This study provides evidence that PM10 and NO2 contribute to lung cancer incidence in Korea.
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참고문헌 (24)
참고문헌 신청
Beelen R / 2008 / Long-term exposure to traffic-related air pollution and lung cancer risk / Epidemiology 19 : 702 ~ 710
Beeson WL / 1998 / Long-term concentrations of ambient air pollutants and incident lung cancer in California adults: results from the AHSMOG study. Adventist Health Study on
Chen F / 2007 / Time trend and geographic patterns of lung adenocarcinoma in the United States, 1973-2002 / Cancer Epidemiol Biomarkers Prev 16 : 2724 ~ 2729
Chen F / 2009 / Lung adenocarcinoma incidence rates and their relation to motor vehicle density / Cancer Epidemiol Biomarkers Prev 18 : 760 ~ 764
Chen G / 2015 / Traffic-related air pollution and lung cancer: a meta-analysis / Thorac Cancer 6 : 307 ~ 318
Beeson WL / 1998 / Long-term concentrations of ambient air pollutants and incident lung cancer in California adults: results from the AHSMOG study. Adventist Health Study on
Chen F / 2007 / Time trend and geographic patterns of lung adenocarcinoma in the United States, 1973-2002 / Cancer Epidemiol Biomarkers Prev 16 : 2724 ~ 2729
Chen F / 2009 / Lung adenocarcinoma incidence rates and their relation to motor vehicle density / Cancer Epidemiol Biomarkers Prev 18 : 760 ~ 764
Chen G / 2015 / Traffic-related air pollution and lung cancer: a meta-analysis / Thorac Cancer 6 : 307 ~ 318
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