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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background: Fracture-risk assessment tool (FRAX) using just clinical risk factors of osteoporosis has been developed to estimate individual risk of osteoporotic fractures. We developed prediction model of fracture risk using bone mineral density (BMD) as well as clinical risk factors in Korean, and assessed the validity of the final model. Methods: To develop and validate an osteoporotic FRAX, a total of 768 Korean men and women aged 50 to 90 years were followed for 7 years in a community-based cohort study. BMD as well as clinical risk factors for osteoporotic fracture including age, sex, body mass index, history of fragility fracture, family history of fracture, smoking status, alcohol intake, use of oral glucocorticoid, rheumatoid arthritis, and other causes of secondary osteoporosis were assessed biannually. Results: During the follow-up period, 86 osteoporotic fractures identified (36 in men and 50 in women). The developed prediction models showed high discriminatory power and had goodness of fit. Conclusions: The developed a Korean specific prediction model for osteoporotic fractures can be easily used as a screening tool to identify individual with high risk of osteoporotic fracture. Further studies for validation are required to confirm the clinical feasibility in general Korean population.
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참고문헌 (21)
참고문헌 신청
Peck WA / 1993 / Consensus development conference: diagnosis, prophylaxis, and treatment of osteoporosis / Am J Med 94:646~650
강번중 / 2012 / Mortality after Hip Fractures in Nonagenarians / 대한골대사학회지 19(2):83~86
윤현구 / 2011 / Incidence and Mortality Following Hip Fracture in Korea / Journal of Korean Medical Science 26(8):1087~1092
Lee YK / 2012 / Mortality after vertebral fracture in Korea : analysis of the National Claim Registry / Osteoporos Int 23:1859~1865
Park C / 2011 / The incidence and residual lifetime risk of osteoporosis-related fractures in Korea / J Bone Miner Metab 29:744~751
강번중 / 2012 / Mortality after Hip Fractures in Nonagenarians / 대한골대사학회지 19(2):83~86
윤현구 / 2011 / Incidence and Mortality Following Hip Fracture in Korea / Journal of Korean Medical Science 26(8):1087~1092
Lee YK / 2012 / Mortality after vertebral fracture in Korea : analysis of the National Claim Registry / Osteoporos Int 23:1859~1865
Park C / 2011 / The incidence and residual lifetime risk of osteoporosis-related fractures in Korea / J Bone Miner Metab 29:744~751
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