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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제18권 제4호
- 발행연도
- 2008.1
- 수록면
- 676 - 681 (6page)
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초록· 키워드
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To obtain a natural antioxidant from a marine biomass, this study investigated the antioxidative activity of methanolic extracts from the marine brown alga, Ishige okamurae collected off Jeju Island. A potent free radical scavenging activity was detected in the ethyl acetate fraction containing polyphenolic compounds, and the potent antioxidant elucidated as a kind of phlorotannin, diphlorethohydroxycarmalol, by NMR and mass spectroscopic data. The free radical scavenging activities of the diphlorethohydroxycarmalol were investigated in relation to 1,1-diphenyl-2-picrylhydrazyl (DPPH), alkyl, and hydroxyl radicals using an electron spin resonance (ESR) system. The diphlorethohydroxycarmalol was found to scavenge DPPH (IC50=3.41 μM) and alkyl (IC50= 4.92 μM) radicals more effectively than the commercial antioxidant, ascorbic acid. Therefore, these results present diphlorethohydroxycarmalol as a new phlorotannin with a potent antioxidative activity that could be useful in cosmetics, foods, and pharmaceuticals.
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참고문헌 (24)
참고문헌 신청
Adebajo, M. O. / 2001 / ESR study of alkyl radicals adsorbed on porous Vycor glass. I. Build-up of methyl and ethyl radicals. Appl. Surf / Sci 171 : 120 ~ 124
Ahn, G. N. / 2007 / Antioxidant activities of phlorotannins purified from Ecklonia cava on free radical scavenging using ESR and H2O2-mediated DNA damage. Eur. Food Res / Tec
Ahn, M. J. / 2006 / Inhibitory activity on HIV-1 reverse transcriptase and integrase of a carmalol derivative from a brown alga, Ishige okamurae. Phytother / Res 20 : 711 ~ 7
Aruoma, O. I. / 1998 / Free radicals, oxidative stress, and antioxidants in human health and disease. J. Am. Oil Chem / Soc 75 : 199 ~ 212
Cahyana, A. H. / 1992 / Pyropheophytin A as an antioxidative substance from the marine alga, Arame (Eicenia bicyclis). Biosci. Biotechnol / Agrochem 56 : 1533 ~ 1535
Ahn, G. N. / 2007 / Antioxidant activities of phlorotannins purified from Ecklonia cava on free radical scavenging using ESR and H2O2-mediated DNA damage. Eur. Food Res / Tec
Ahn, M. J. / 2006 / Inhibitory activity on HIV-1 reverse transcriptase and integrase of a carmalol derivative from a brown alga, Ishige okamurae. Phytother / Res 20 : 711 ~ 7
Aruoma, O. I. / 1998 / Free radicals, oxidative stress, and antioxidants in human health and disease. J. Am. Oil Chem / Soc 75 : 199 ~ 212
Cahyana, A. H. / 1992 / Pyropheophytin A as an antioxidative substance from the marine alga, Arame (Eicenia bicyclis). Biosci. Biotechnol / Agrochem 56 : 1533 ~ 1535
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