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ObjectiveTo assess the correlation between different pain symptoms and different domains of women's health-related qualityof life (HRQoL). MethodsSeventy-seven women with deep infiltrating endometriosis were successively enrolled between June 2011 and August2013 while being prepared to undergo laparoscopy due to pain and/or infertility. We quantified the intensities ofdysmenorrhea, deep dyspareunia, chronic pelvic pain, and dyschezia (menstrual and non-menstrual) using a 11-pointvisual analog scale (VAS: 0–10) and the validated full versions of the Short Form 36 (SF36) and Endometriosis HealthProfile (EHP30) questionnaires to assess HRQoL. The pain symptoms were considered simultaneously in a hierarchicalagglomerative clustering method (exploratory multivariate approach) and the associations among scores were testedby bivariate correlation. ResultsDysmenorrhea showed the lowest similarity on to the multivariate cluster analysis and no statistically significantcorrelation with the other pain symptoms: deep dyspareunia (P=0.244), chronic pelvic pain (P=0.108), menstrualdyschezia (P=0.238), and non-menstrual dyschezia (P=0.380). Dysmenorrhea and chronic pelvic pain were the mainsymptoms correlated with all domains of the SF36 and the EHP30 (core instrument) questionnaires (P<0.05). ConclusionDysmenorrhea and chronic pelvic pain were independent factors associated with HRQoL.

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