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논문 기본 정보

자료유형
학술저널
저자정보
강성희 (연세대학교) 김문영 (연세대학교) 백순구 (연세대학교)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.33 No.50
발행연도
2018.1
수록면
1 - 2 (2page)

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초록· 키워드

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Sarcopenia is a syndrome characterized by skeletal muscle loss with aging, which is prevalent in adults with cancer and those with chronic comorbidities such as liver cirrhosis.1 The prevalence of concomitant sarcopenia is reported to be > 40% in cirrhosis.2 Sarcopenia has emerged as an important and novel prognostic predictor in a variety of clinical conditions. Several studies have reported that sarcopenia is associated with a poor prognosis, as well as reduced survival, before and after liver transplantation. Moreover, the model for end-stage liver disease (MELD)—sarcopenia score, which combines MELD score and the psoas muscle area score, was found to be better than the MELD scores in predicting waiting-list mortality, and its predictive value was found to be superior to that of the MELD score in several studies.3 However, there were few studies that performed repeat skeletal muscle area measurements using serial imaging. Then, it is not known whether the rate of skeletal muscle depletion is associated with a poor prognosis in patients with liver cirrhosis.

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