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학술저널
저자정보
Won Seok Choi (Hanyang University Guri Hospital) 한동수 (한양대학교) 은창수 (한양대학교) Dong Il Park (Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine) Jeong-Sik Byeon (Asan Medical Center University of Ulsan College of Medicine) Dong-Hoon Yang (University of Ulsan College of Medicine) Sung-Ae Jung (Ewha Womans University School of Medicine) 이상길 (연세대학교) 홍성필 (연세대학교) Cheol Hee Park (Hallym University Medical Center) Suck-Ho Lee (Soonchunhyang University College of Medicine) Jeong-Seon Ji (The Catholic University of Korea Incheon St. Mary’s Hospital) Sung Jae Shin (Ajou University School of Medinie) Bora Keum (Korea University College of Medicine) Hyun Soo Kim (Yonsei University College of Medicine) Jung Hye Choi (Hanyang University Guri Hospital) Sin-Ho Jung (Duke University)
저널정보
대한장연구학회 Intestinal research Intestinal research Vol.16 No.1
발행연도
2018.1
수록면
126 - 133 (8page)

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Background/Aims: Colonoscopic surveillance is currently recommended after polypectomy owing to the risk of newly developed colonic neoplasia. However, few studies have investigated colonoscopy surveillance in Asia. This multicenter and prospective study was undertaken to assess the incidence of advanced adenoma based on baseline adenoma findings at 3 yearsafter colonoscopic polypectomy. Methods: A total of 1,323 patients undergoing colonoscopic polypectomy were prospectivelyassigned to 3-year colonoscopy surveillance at 11 tertiary endoscopic centers. Relative risks for advanced adenoma after 3 years were calculated according to baseline adenoma characteristics. Results: Among 1,323 patients enrolled, 387 patients (29.3%) were followed up, and the mean follow-up interval was 31.0±9.8 months. The percentage of patients with advanced adenoma on baseline colonoscopy was higher in the surveillance group compared to the non-surveillance group (34.4% vs. 25.7%). Advanced adenoma recurrence was observed in 17 patients (4.4%) at follow-up. The risk of advanced adenoma recurrence was 2 times greater in patients with baseline advanced adenoma than in those with baseline non-advanced adenoma,though the difference was not statistically significant (6.8% [9/133] vs. 3.1% [8/254], P =0.09). Advanced adenoma recurrencewas observed only in males and in subjects aged ≥50 years. In contrast, adenoma recurrence was observed in 187 patients (48.3%) at follow-up. Male sex, older age (≥50 years), and multiple adenomas (≥3) at baseline were independent risk factors foradenoma recurrence. Conclusions: A colonoscopy surveillance interval of 3 years in patients with baseline advanced adenomacan be considered appropriate.

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