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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 219 - 236 (18page)
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초록· 키워드
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Cancer is currently a leading cause of deaths worldwide and the number of new cases is growing rapidly in both, developed and developing countries. Nutritional management during and after cancer treatment affects treatment efficacy and patient quality of life (QOL). This review systemically examined the effect of oral nutritional interventions on nutritional and clinical outcomes in cancer patients. We especially focused on outcomes such as nutritional status indices, immune-associated biochemical markers, and QOL assessments to provide insights on the applicability of different outcomes. A total of 28 papers were selected for systematic review. The nutritional composition of oral nutritional supplements (ONS), outcome measures, and efficacy of the oral nutritional interventions were summarized and discussed. Most ONS contain 1 or more functional components in addition to basic nutrients. Each study used various outcome measures and significant efficacy was observed for a limited number of measures. Nutritional status indices, QOL measures, and the duration of hospital stay improved in about 40% of the studies. One or more markers of immune function and inflammatory responses were improved by ONS in 65% of the selected studies. These results suggest that appropriate use of ONS may be an ideal way to improve treatment efficacy; however, additional intervention trials are required to confirm these findings.
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참고문헌 (91)
참고문헌 신청
Ferlay J / 2015 / Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012 / Int J Cancer 136:E359~E386
Santarpia L / 2011 / Nutritional screening and early treatment of malnutrition in cancer patients / J Cachexia Sarcopenia Muscle 2:27~35
Macciò A / 2012 / A randomized phase III clinical trial of a combined treatment for cachexia in patients with gynecological cancers : evaluating the impact on metabolic and inflammatory profiles and quality of life / Gynecol Oncol 124:417~425
Van Cutsem E / 2005 / The causes and consequences of cancer-associated malnutrition / Eur J Oncol Nurs 9(Suppl 2):S51~S63
Caccialanza R / 2016 / Nutritional support in cancer patients : a position paper from the Italian Society of Medical Oncology(AIOM)and the Italian Society of Artificial Nutrition and Metabolism(SINPE) / J Cancer 7:131~135
Santarpia L / 2011 / Nutritional screening and early treatment of malnutrition in cancer patients / J Cachexia Sarcopenia Muscle 2:27~35
Macciò A / 2012 / A randomized phase III clinical trial of a combined treatment for cachexia in patients with gynecological cancers : evaluating the impact on metabolic and inflammatory profiles and quality of life / Gynecol Oncol 124:417~425
Van Cutsem E / 2005 / The causes and consequences of cancer-associated malnutrition / Eur J Oncol Nurs 9(Suppl 2):S51~S63
Caccialanza R / 2016 / Nutritional support in cancer patients : a position paper from the Italian Society of Medical Oncology(AIOM)and the Italian Society of Artificial Nutrition and Metabolism(SINPE) / J Cancer 7:131~135
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