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논문 기본 정보

자료유형
학술저널
저자정보
이규완 (City of Hope Comprehensive Cancer Center Duarte CA USA)
저널정보
대한스포츠의학회 대한스포츠의학회지 대한스포츠의학회지 제39권 제3호
발행연도
2021.9
수록면
77 - 90 (14page)
DOI
10.5763/kjsm.2021.39.3.77

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초록· 키워드

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Conventional treatments accessible to breast cancer survivors after diagnosis include cancer therapies with cardiotoxic effects such as trastuzumab and/or anthracycline-based chemotherapy, which can result in undesirable cardiac injuries known as cancer therapy-induced cardiotoxicity. Cancer therapy-induced cardiotoxicity is among a variety of cardiovascular comorbidities responsible for increased mortality in cancer survivors, and when accompanied by preexisting cardiovascular comorbidities, this detrimental side effect becomes a major health concern. Breast cancer survivors may be predisposed to this additional concern due to preexisting comorbidities related to cardiovascular diseases such as obesity, hypertension, and type 2 diabetes. Research in the rapidly emerging field of study which focuses on improving cardiovascular health in cancer survivors, known as cardio-oncology, reveals that exercise can improve the aforementioned comorbidities in clinical settings. However, the evidence has not been comprehensively evaluated to prescribe exercise as a clinical therapeutic option to improve cardiovascular health in breast cancer survivors. Therefore, the purpose of this review is to summarize the current evidence on the effects of exercise on cardiovascular outcomes in women with breast cancer at three different time points; before, during, and after cancer therapy. In addition, current knowledge gaps and future directions in the field of exercise science and cardio-oncology will be addressed.

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