지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.8
- 수록면
- 141 - 145 (5page)
- DOI
- https://doi.org/10.11005/jbm.2017.24.3.141
이용수
초록· 키워드
오류제보하기
An adequate supply of vitamin D is considered necessary for osteoporosis management and fracture prevention. Intermittent high-dose vitamin D supplementation is an effective and convenient way to achieve and maintain sufficient vitamin D status. However, the long-term effectiveness of supplementation for preventing falls and fractures is unclear, and some deleterious effects of such treatments have been reported. Concerning these issues, the Korean Society for Bone and Mineral Research task force team reviewed previous clinical trials and provided the following perspectives based on current evidence: 1) An adequate supply of vitamin D is necessary for preventing falls and fractures in postmenopausal women and men older than 50 years. An oral intake of 800 to 1,000 IU/day of vitamin D is generally recommended. 2) Care should be taken concerning the routine use of intermittent high-dose vitamin D, as large-scale clinical trials showed increased risk of falls or fractures after high-dose vitamin D administration. Intermittent high-dose vitamin D supplementation is recommendable only in cases of malabsorption or when oral administration is not suitable. 3) Monitoring of the serum level of 25-hydroxy-vitamin D (25[OH]D) is advisable, especially when intermittent high-dose vitamin D is used for supplementation. The task force team suggests that a serum 25(OH)D level of >20 ng/mL is generally appropriate for the prevention of osteoporosis, and that a serum 25(OH)D level of >30 ng/mL is probably helpful both for the management of osteoporosis and the prevention of fractures and falls. However, serum 25(OH)D level >50 ng/mL (this value can vary depending on the measurement method used) is unnecessary and may be undesirable. These perspectives are relevant for the management of osteoporosis, falls, or fractures. Other metabolic bone diseases or non-skeletal disorders are not within the scope of these perspectives.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Holick MF / 2011 / Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline / J Clin Endocrinol Metab 96:1911~1930
Deluca HF / 2014 / History of the discovery of vitamin D and its active metabolites / Bonekey Rep 3:479
Institute of Medicine, Food and Nutrition Board / 2010 / Dietary reference intakes for calcium and vitamin D / National Academy Press
Lips P / 2006 / The prevalence of vitamin D inadequacy amongst women with osteoporosis: an international epidemiological investigation / J Intern Med 260:245~254
Yoshimura N / 2013 / Profiles of vitamin D insufficiency and deficiency in Japanese men and women: association with biological, environmental, and nutritional factors and coexisting disorders: the ROAD study / Osteoporos Int 24:2775~2787
Deluca HF / 2014 / History of the discovery of vitamin D and its active metabolites / Bonekey Rep 3:479
Institute of Medicine, Food and Nutrition Board / 2010 / Dietary reference intakes for calcium and vitamin D / National Academy Press
Lips P / 2006 / The prevalence of vitamin D inadequacy amongst women with osteoporosis: an international epidemiological investigation / J Intern Med 260:245~254
Yoshimura N / 2013 / Profiles of vitamin D insufficiency and deficiency in Japanese men and women: association with biological, environmental, and nutritional factors and coexisting disorders: the ROAD study / Osteoporos Int 24:2775~2787
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