지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Caffeine citrate is used as standard therapy for apnea of prematurity. The optimum dose and timing of caffeine therapy are controversial. The purpose of this article is to review therapeutic indications, influence on neonatal outcomes, and long-term effects of caffeine in preterm infants.
Currently, the approved indications of caffeine citrate in Korea are the treatment of documented apnea and prevention of extubation failure. High doses of caffeine have been shown to improve acute outcomes such as a reduction in the frequency of apnea, days of documented apnea and extubation failure. Early caffeine therapy is associated with improvements in bronchopulmonary dysplasia and patent ductus arteriosus. However, an increased incidence of necrotizing enterocolitis in neonates receiving early caffeine therapy was reported. Additional research is needed to evaluate the longterm effects associated with high doses of caffeine. The recommendation of early caffeine prophylaxis in preterm infants also requires further study.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Poets C.F. / 1994 / Epidemiology and pathophysiology of apnea of prematurity / Biol Neonate 65(3-4):211~219
김태형 / 2014 / Morbidity of Low Birth Weight Infants in Korea (2012): A Comparison with Japan and the USA / Neonatal medicine 21(4):218~223
Schmidt B. / 2006 / Caffeine therapy for apnea of prematurity / N Engl J Med 354(20):2112~2121
Natarajan G. / 2007 / Therapeutic drug monitoring for caffeine in preterm neonates: an unnecessary exercise? / Pediatrics 119:936~940
Henderson-Smart D.J. / 2010 / Prophylactic methylxanthines for endotracheal extubation in preterm infants / Cochrane Database Syst Rev 8(12):CD000139
김태형 / 2014 / Morbidity of Low Birth Weight Infants in Korea (2012): A Comparison with Japan and the USA / Neonatal medicine 21(4):218~223
Schmidt B. / 2006 / Caffeine therapy for apnea of prematurity / N Engl J Med 354(20):2112~2121
Natarajan G. / 2007 / Therapeutic drug monitoring for caffeine in preterm neonates: an unnecessary exercise? / Pediatrics 119:936~940
Henderson-Smart D.J. / 2010 / Prophylactic methylxanthines for endotracheal extubation in preterm infants / Cochrane Database Syst Rev 8(12):CD000139
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