지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 102 - 107 (6page)
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초록· 키워드
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We report a case of bilateral femur fracture which may have resulted in part from long-term administration of antipsychotic agents. A 43-year-old female patient with pain in both thighs visited our clinic. We conducted Xray and magnetic resonance imaging (MRI) examinations which revealed bilateral femur fractures. The right proximal femur had a complete fracture, and the left proximal femur had an incomplete fracture, both of which were in the subtrochanteric area. The patient was treated by intramedullary nailing in the right femur. Laboratory analysis showed hyperprolactinemia and hypogonadism. Bone mineral density analysis showed osteoporosis. Antipsychotic drug-induced hyperprolactinemia is a well-known phenomenon. Despite concerns about hyperprolactinemia induced osteoporotic fracture in patients treated with only prolactin-elevating medications, the issue has not been extensively studied. If hyperprolactinemia patients suffer from uncontrolled pain, we recommend MRI examination as surgeons should be aware of the possibility of osteoporotic fracture induced by hyperprolactinemia.
목차
등록된 정보가 없습니다.
참고문헌 (14)
참고문헌 신청
Rothman MS / 2008 / Female hypogonadism : evaluation of the hypothalamic-pituitary-ovarian axis / Pituitary 11:163~169
Molitch ME / 1999 / Medical treatment of prolactinomas / Endocrinol Metab Clin North Am 28:143~169
De Hert M / 2016 / Relationship between antipsychotic medication, serum prolactin levels and osteoporosis/osteoporotic fractures in patients with schizophrenia : a critical literature review / Expert Opin Drug Saf 15:809~823
Molitch ME / 2008 / Drugs and prolactin / Pituitary 11:209~218
Petty RG / 1999 / Prolactin and antipsychotic medications: mechanism of action / Schizophr Res 35(Suppl):S67~S73
Molitch ME / 1999 / Medical treatment of prolactinomas / Endocrinol Metab Clin North Am 28:143~169
De Hert M / 2016 / Relationship between antipsychotic medication, serum prolactin levels and osteoporosis/osteoporotic fractures in patients with schizophrenia : a critical literature review / Expert Opin Drug Saf 15:809~823
Molitch ME / 2008 / Drugs and prolactin / Pituitary 11:209~218
Petty RG / 1999 / Prolactin and antipsychotic medications: mechanism of action / Schizophr Res 35(Suppl):S67~S73
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